PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27754854-15	2017	An alternative pathway by which metformin exerted its action was through downregulation of IGFBP-2 in DU145 and LNCaP cells, independently of AMPK.	Metformin	32-41	insulin like growth factor binding protein 2	Homo sapiens	91-98	
27009398-7	2016	Finally, when compared to untreated type 2 diabetes patients, the metformin-treated diabetic patients showed increased IGFBP-2 levels with diminished serum IGF-1 levels.	Metformin	66-75	insulin like growth factor binding protein 2	Homo sapiens	119-126	
25687657-9	2015	Higher concentrations of metformin lead to a significant (p < 0.05) dose-dependent attenuation of the progesterone effect with regard to IGFBP-1, -3, -5, -6, as well as IGF I receptor, while it did not change the expression of IGFBP-2 and -4, IGF I and II and the IGF II receptor.	Metformin	25-34	insulin like growth factor binding protein 2	Homo sapiens	230-244