PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35603556-0 2022 Metformin suppresses lung adenocarcinoma by downregulating long non-coding RNA (lncRNA) AFAP1-AS1 and secreted phosphoprotein 1 (SPP1) while upregulating miR-3163. Metformin 0-9 secreted phosphoprotein 1 Homo sapiens 102-127 35603556-0 2022 Metformin suppresses lung adenocarcinoma by downregulating long non-coding RNA (lncRNA) AFAP1-AS1 and secreted phosphoprotein 1 (SPP1) while upregulating miR-3163. Metformin 0-9 secreted phosphoprotein 1 Homo sapiens 129-133 31293042-11 2019 Furthermore, 50 muM metformin significantly upregulated the gene expression levels of ALP, BSP, OPN, OCN, and Runx2 and the protein expression of ALP and Runx2 (P < 0.05). Metformin 20-29 secreted phosphoprotein 1 Homo sapiens 96-99 29679571-4 2018 Our results showed that metformin ameliorated TGF-beta1-induced production of osteogenic proteins Runx2 and osteopontin as well as calcium deposition in the cultured human AVICs. Metformin 24-33 secreted phosphoprotein 1 Homo sapiens 108-119 28025449-8 2017 Treatment for seven days with metformin increased the expression levels of osteogenic protein mRNAs, including alkaline phosphatase, runt-related transcription factor 2, and osteopontin. Metformin 30-39 secreted phosphoprotein 1 Homo sapiens 174-185