PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26304716-4 2015 Mechanistically, metformin caused abrogation of the G2 checkpoint and increase of mitotic catastrophe, associated with suppression of Wee1 kinase and in turn CDK1 Tyr15 phosphorylation. Metformin 17-26 WEE1 G2 checkpoint kinase Homo sapiens 134-138 26304716-6 2015 Finally, metformin-mediated AMPK/mTOR/p70S6K was identified as a possible upstream pathway controlling translational regulation of Wee1 and Rad51. Metformin 9-18 WEE1 G2 checkpoint kinase Homo sapiens 131-135