PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23083540-0	2013	Metformin alters the insulin signaling pathway in ischemic cardiac tissue in a swine model of metabolic syndrome.	Metformin	0-9	insulin	Sus scrofa	21-28	
23083540-1	2013	OBJECTIVE: The purpose of this study is to evaluate the effect of metformin on insulin signaling in ischemic cardiac tissue in a swine model of metabolic syndrome.	Metformin	66-75	insulin	Sus scrofa	79-86	
23083540-11	2013	CONCLUSIONS: Metformin treatment in the context of metabolic syndrome and myocardial ischemia dramatically upregulates the insulin signaling pathway in chronically ischemic myocardium, which is at the crossroads of known metabolic and survival benefits of metformin.	Metformin	13-22	insulin	Sus scrofa	123-130	
23083540-11	2013	CONCLUSIONS: Metformin treatment in the context of metabolic syndrome and myocardial ischemia dramatically upregulates the insulin signaling pathway in chronically ischemic myocardium, which is at the crossroads of known metabolic and survival benefits of metformin.	Metformin	256-265	insulin	Sus scrofa	123-130	
433615-0	1979	The effect of metformin on the arginine induced insulin- and glucagon release in pigs.	Metformin	14-23	insulin	Sus scrofa	48-55	
22048751-5	2012	The hypothesis was disproved, as we have shown that insulin and metformin, like insulin, directly stimulate NO production by endothelium of a conduit artery; this function may be of value in delaying the atherothrombotic process.	Metformin	64-73	insulin	Sus scrofa	80-87	
16784971-8	2006	Metformin vs placebo treatment of diabetic pigs (twice 1.5 g/d) for 2 weeks during isoenergetic feeding (1045 kJ/kg body weight(0.75)) resulted in a reduction in both fasting and postprandial hyperglycemia (14.7 +/- 1.5 vs 19.4 +/- 0.6 and 24.9 +/- 2.2 vs 35.5 +/- 4.9 mmol/L), a reduction in daily urinary glucose excretion (approximately 250 vs approximately 350 g/kg food), and an increase in insulin-stimulated glucose disposal (9.4 +/- 2.2 vs 5.8 +/- 1.7 mg kg(-1) min(-1); P < .05), respectively.	Metformin	0-9	insulin	Sus scrofa	396-403