PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24756098-5 2014 The aim of this study was to investigate whether exercise training and/or metformin improve glucose homeostasis and albuminuria and downregulate renal ADAM17 and ACE2 shedding in db/db mice. Metformin 74-83 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Mus musculus 162-166 24756098-12 2014 In conclusion, exercise training alone and in combination with metformin prevented shedding of renal ACE2 by decreasing ADAM17 protein. Metformin 63-72 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Mus musculus 101-105