PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9109854-0 1997 Metformin therapy is associated with a decrease in plasma plasminogen activator inhibitor-1, lipoprotein(a), and immunoreactive insulin levels in patients with the polycystic ovary syndrome. Metformin 0-9 lipoprotein(a) Homo sapiens 93-107 16882108-19 2006 However, long-term treatment with metformin plus pioglitazone significantly reduced Lp(a) plasma levels, whereas metformin + rosiglitazone did not. Metformin 34-43 lipoprotein(a) Homo sapiens 84-89 16882108-20 2006 CONCLUSION: For patients with type 2 diabetes mellitus and metabolic syndrome, combined treatment with metformin and rosiglitazone or pioglitazone is safe and effective, However, the pioglitazone combination also reduced the plasma Lp(a) levels whereas the rosiglitazone combination did not. Metformin 103-112 lipoprotein(a) Homo sapiens 232-237 9109854-6 1997 Metformin decreases Izero in hyperinsulinemic PCOS patients, reverses the hyperinsulinemia-driven endocrinopathy, decreases PAI-1, and decreases Lp(a), and should thus reduce the increased risk of atherothrombosis in PCOS. Metformin 0-9 lipoprotein(a) Homo sapiens 145-150