PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33194016-0	2020	Metformin upregulates the expression of Gli1 in vascular endothelial cells in hyperoxia-exposed neonatal mice.	Metformin	0-9	GLI-Kruppel family member GLI1	Mus musculus	40-44	
33194016-14	2020	Furthermore, both immunofluorescence staining and FCM demonstrated that metformin increased Gli1 expression in vascular endothelial cells.	Metformin	72-81	GLI-Kruppel family member GLI1	Mus musculus	92-96	
33194016-16	2020	These results indicated that metformin enhanced lung vascular development and upregulated the expression of Gli1 in the pulmonary vascular endothelial cells in hyperoxic neonatal mice.	Metformin	29-38	GLI-Kruppel family member GLI1	Mus musculus	108-112	
30653446-8	2019	Furthermore, GLI-family (transcription factors of the Hh pathway) knockdown in HUVECs and retinal vasculature revealed that downregulation of hyperglycemia-activated autophagy by the metformin-mediated Hh pathway activation was GLI1 dependent.	Metformin	183-192	GLI-Kruppel family member GLI1	Mus musculus	228-232	
34910358-10	2022	Metformin downregulated Gli1 expression in macrophages in the lung after exposure to hyperoxia on postnatal day 14.	Metformin	0-9	GLI-Kruppel family member GLI1	Mus musculus	24-28	
34910358-11	2022	In vitro studies showed that metformin inhibited Gli1 expression in RAW264.7 macrophages exposed to 90% oxygen, which was reversed after purmorphamine pretreatment.	Metformin	29-38	GLI-Kruppel family member GLI1	Mus musculus	49-53