PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29040818-15	2017	Metformin prevented the THAP-induced mitochondrial dysfunction and reduced CHOP content in cytosol and nucleus.	Metformin	0-9	DNA-damage inducible transcript 3	Mus musculus	75-79	
29040818-16	2017	Thus, metformin reduces cardiac injury during ER stress through the protection of cardiac mitochondria and attenuation of CHOP expression.	Metformin	6-15	DNA-damage inducible transcript 3	Mus musculus	122-126	
32189544-9	2020	Furthermore, 50mg/kg metformin markedly down-regulated the expression of proinflammatory cytokines (TNF-alpha and IL-1beta) and ER stress related genes (ATF4, ATF6, XBP1, Grp78 and CHOP) in rotenone-induced PD mice.	Metformin	21-30	DNA-damage inducible transcript 3	Mus musculus	181-185	
33746115-13	2021	The contents of CHOP and cleaved ATF6 were decreased in metformin-treated 24 mo.	Metformin	56-65	DNA-damage inducible transcript 3	Mus musculus	16-20	
32694673-6	2019	In primary mouse hepatocytes, metformin stimulates the secretion of GDF15 by increasing the expression of activating transcription factor 4 (ATF4) and C/EBP homologous protein (CHOP; also known as DDIT3).	Metformin	30-39	DNA-damage inducible transcript 3	Mus musculus	151-175	
32694673-6	2019	In primary mouse hepatocytes, metformin stimulates the secretion of GDF15 by increasing the expression of activating transcription factor 4 (ATF4) and C/EBP homologous protein (CHOP; also known as DDIT3).	Metformin	30-39	DNA-damage inducible transcript 3	Mus musculus	177-181	
32694673-6	2019	In primary mouse hepatocytes, metformin stimulates the secretion of GDF15 by increasing the expression of activating transcription factor 4 (ATF4) and C/EBP homologous protein (CHOP; also known as DDIT3).	Metformin	30-39	DNA-damage inducible transcript 3	Mus musculus	197-202