PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32694673-6 2019 In primary mouse hepatocytes, metformin stimulates the secretion of GDF15 by increasing the expression of activating transcription factor 4 (ATF4) and C/EBP homologous protein (CHOP; also known as DDIT3). Metformin 30-39 DNA-damage inducible transcript 3 Mus musculus 151-175 33746115-13 2021 The contents of CHOP and cleaved ATF6 were decreased in metformin-treated 24 mo. Metformin 56-65 DNA-damage inducible transcript 3 Mus musculus 16-20 32189544-9 2020 Furthermore, 50mg/kg metformin markedly down-regulated the expression of proinflammatory cytokines (TNF-alpha and IL-1beta) and ER stress related genes (ATF4, ATF6, XBP1, Grp78 and CHOP) in rotenone-induced PD mice. Metformin 21-30 DNA-damage inducible transcript 3 Mus musculus 181-185 32694673-6 2019 In primary mouse hepatocytes, metformin stimulates the secretion of GDF15 by increasing the expression of activating transcription factor 4 (ATF4) and C/EBP homologous protein (CHOP; also known as DDIT3). Metformin 30-39 DNA-damage inducible transcript 3 Mus musculus 177-181 32694673-6 2019 In primary mouse hepatocytes, metformin stimulates the secretion of GDF15 by increasing the expression of activating transcription factor 4 (ATF4) and C/EBP homologous protein (CHOP; also known as DDIT3). Metformin 30-39 DNA-damage inducible transcript 3 Mus musculus 197-202 29040818-15 2017 Metformin prevented the THAP-induced mitochondrial dysfunction and reduced CHOP content in cytosol and nucleus. Metformin 0-9 DNA-damage inducible transcript 3 Mus musculus 75-79 29040818-16 2017 Thus, metformin reduces cardiac injury during ER stress through the protection of cardiac mitochondria and attenuation of CHOP expression. Metformin 6-15 DNA-damage inducible transcript 3 Mus musculus 122-126