PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11976274-9 2002 In SHR chronically treated with dimethylthiourea endothelium-dependent contractions to acetylcholine were decreased, and reduced further by acute in vitro exposure to deferoxamine or the combination of superoxide dismutase plus catalase. 1,3-dimethylthiourea 32-48 catalase Rattus norvegicus 228-236 20430163-6 2010 The capillary filtration coefficient (P<.01), LW/BW (P<.01) and PCBAL (P<.05) were significantly lower among the DMTU-treated rats than hosts pretreated with SOD or CAT. 1,3-dimethylthiourea 122-126 catalase Rattus norvegicus 174-177 11162780-8 2001 Furthermore, coincubation of 2 mM nickel subsulfide with catalase, dimethylthiourea, mannitol, or vitamin C at 37 degrees C for 2 h resulted in a significant decrease of nickel subsulfide-induced formation of DPXLs, suggesting that nickel subsulfide-induced DPXLs formation in isolated rat lymphocytes is caused by the formation of ROS. 1,3-dimethylthiourea 67-83 catalase Rattus norvegicus 57-65 1960147-5 1991 Specific scavenging of free radical activity by the enzymes catalase and superoxide dismutase, the hydroxyl radical inhibitors dimethyl sulfoxide and dimethylthiourea (DMTU) and by chelation of intracellular free iron with deferoxamine produced only a partial restoration of [3H]thymidine incorporation into DNA, which was maximal for DMTU (30% of normal incorporation). 1,3-dimethylthiourea 150-166 catalase Rattus norvegicus 60-68 1960147-5 1991 Specific scavenging of free radical activity by the enzymes catalase and superoxide dismutase, the hydroxyl radical inhibitors dimethyl sulfoxide and dimethylthiourea (DMTU) and by chelation of intracellular free iron with deferoxamine produced only a partial restoration of [3H]thymidine incorporation into DNA, which was maximal for DMTU (30% of normal incorporation). 1,3-dimethylthiourea 335-339 catalase Rattus norvegicus 60-68 2821829-3 1987 We found that addition of glucose oxidase (GO) or H2O2 to isolated perfused rat kidneys caused injury that was manifested by decreases in glomerular filtration rate, perfusion flow rate, and sodium reabsorption and that was prevented by addition of catalase (CAT) (but not inactivated CAT) or large doses of DMTU (15 mM), but not urea (15 mM). 1,3-dimethylthiourea 308-312 catalase Rattus norvegicus 249-257