PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11597127-0 2001 TNFalpha enhances the DNA single-strand breakage induced by the short-chain lipid hydroperoxide analogue tert-butylhydroperoxide via ceramide-dependent inhibition of complex III followed by enforced superoxide and hydrogen peroxide formation. tert-Butylhydroperoxide 105-128 tumor necrosis factor Homo sapiens 0-8 29253822-7 2018 Cell aggregation as well as the down-regulation of IL-1beta, TNFalpha and PGE2 caused by the culture on collagen I-coated surface were suppressed by ROS donor, tert-butylhydroperoxide (tBHP). tert-Butylhydroperoxide 160-183 tumor necrosis factor Homo sapiens 61-69 29253822-7 2018 Cell aggregation as well as the down-regulation of IL-1beta, TNFalpha and PGE2 caused by the culture on collagen I-coated surface were suppressed by ROS donor, tert-butylhydroperoxide (tBHP). tert-Butylhydroperoxide 185-189 tumor necrosis factor Homo sapiens 61-69 11597127-1 2001 Treatment of U937 cells with nontoxic concentrations of TNFalpha increased the DNA strand scission induced by a short-chain lipid hydroperoxide analogue, tert-butylhydroperoxide. tert-Butylhydroperoxide 154-177 tumor necrosis factor Homo sapiens 56-64 11597127-4 2001 Three lines of evidence support this inference: (a) a synthetic cell-permeable ceramide analogue reproduced all the effects of TNFalpha, (b) TNFalpha promoted the formation of ceramide via a mechanism sensitive to inhibition of sphingomyelinases by tricyclodecan-9-yl-xanthogenate and imipramine, and (c) the TNFalpha-mediated enhancement of the tert-butylhydroperoxide-induced DNA-damaging response was prevented under conditions in which ceramide formation was inhibited. tert-Butylhydroperoxide 346-369 tumor necrosis factor Homo sapiens 141-149 11597127-4 2001 Three lines of evidence support this inference: (a) a synthetic cell-permeable ceramide analogue reproduced all the effects of TNFalpha, (b) TNFalpha promoted the formation of ceramide via a mechanism sensitive to inhibition of sphingomyelinases by tricyclodecan-9-yl-xanthogenate and imipramine, and (c) the TNFalpha-mediated enhancement of the tert-butylhydroperoxide-induced DNA-damaging response was prevented under conditions in which ceramide formation was inhibited. tert-Butylhydroperoxide 346-369 tumor necrosis factor Homo sapiens 141-149