PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9221835-4 1997 Net TGF-beta1 production in injured RPTC increased 1.7- and 3.2-fold on Days 1 and 2, respectively, and returned to control levels 4 days following TBHP treatment. tert-Butylhydroperoxide 148-152 transforming growth factor beta 1 Homo sapiens 4-13 9221835-5 1997 An anti-TGF-beta antibody increased monolayer confluence to 50% and DNA content 1.3-fold 4 days after TBHP exposure. tert-Butylhydroperoxide 102-106 transforming growth factor beta 1 Homo sapiens 8-16 9221835-8 1997 The results demonstrate that TBHP-induced injury increases net TGF-beta1 production in RPTC and that autocrine TGF-beta1 inhibits regeneration of the monolayer by potentiating cellular injury and monolayer deterioration. tert-Butylhydroperoxide 29-33 transforming growth factor beta 1 Homo sapiens 63-72 8631767-5 1996 Studies performed to analyze levels of c-fos mRNA, a gene whose expression is modulated by redox state, demonstrated that only high, apoptotic concentrations of TGF-beta (2.5 ng/ml) produced an increase in the mRNA levels of this gene, the level of induction being similar to that found when cells were incubated in the presence of tert-butyl hydroperoxide. tert-Butylhydroperoxide 332-356 transforming growth factor beta 1 Homo sapiens 161-169 32471991-7 2020 Furthermore, TGF-beta1 increased reactive oxygen species (ROS) levels in PLC/PRF/5 cells and enhanced tert-butyl hydroperoxide-induced ROS levels in Huh7 cells; these changes were reversed by xCT overexpression. tert-Butylhydroperoxide 102-126 transforming growth factor beta 1 Homo sapiens 13-22