PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30414849-4	2019	METHODS: TFEB activity was detected in NP tissues in puncture-induced rat IVDD model by immunofluorescence as well as in tert-Butyl hydroperoxide (TBHP), the reactive oxygen species (ROS) donor to induce oxidative stress, treated NP cells by western blot.	tert-Butylhydroperoxide	121-145	transcription factor EB	Rattus norvegicus	9-13	
35096819-6	2021	Mechanistically, we found that TBHP may induce autophagosome and lysosome fusion interruption and lysosomal dysfunction, while apigenin alleviates these phenomena by promoting the nuclear translocation of TFEB via the AMPK/mTOR signaling pathway.	tert-Butylhydroperoxide	31-35	transcription factor EB	Rattus norvegicus	205-209	
30414849-7	2019	RESULTS: The nuclear localization of TFEB declined in degenerated rat NP tissue as well as in TBHP treated NP cells.	tert-Butylhydroperoxide	94-98	transcription factor EB	Rattus norvegicus	37-41	
30414849-8	2019	Applying lentivirus to transfect NP cells, TFEB overexpression restored the TBHP-induced autophagic flux blockage and protected NP cells against apoptosis and senescence; these protections of TFEB are diminished by chloroquine-medicated autophagy inhibition.	tert-Butylhydroperoxide	76-80	transcription factor EB	Rattus norvegicus	43-47	
30414849-8	2019	Applying lentivirus to transfect NP cells, TFEB overexpression restored the TBHP-induced autophagic flux blockage and protected NP cells against apoptosis and senescence; these protections of TFEB are diminished by chloroquine-medicated autophagy inhibition.	tert-Butylhydroperoxide	76-80	transcription factor EB	Rattus norvegicus	192-196	
30414849-11	2019	TFEB overexpression suppressed TBHP-induced apoptosis and senescence via autophagic flux stimulation in NP cell and alleviates puncture-induced IVDD development in vivo.	tert-Butylhydroperoxide	31-35	transcription factor EB	Rattus norvegicus	0-4	
30414849-4	2019	METHODS: TFEB activity was detected in NP tissues in puncture-induced rat IVDD model by immunofluorescence as well as in tert-Butyl hydroperoxide (TBHP), the reactive oxygen species (ROS) donor to induce oxidative stress, treated NP cells by western blot.	tert-Butylhydroperoxide	147-151	transcription factor EB	Rattus norvegicus	9-13