PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32542535-6 2020 Exposure to 50 muM TBHP increased caspase 3/7 activity, an indicator of apoptosis, after 8 and 24 h. Antioxidant treatment markedly reduced TBHP-stimulated caspase 3/7 activity, PGE2 release, and IL-6 release. tert-Butylhydroperoxide 19-23 interleukin 6 Homo sapiens 196-200 32542535-6 2020 Exposure to 50 muM TBHP increased caspase 3/7 activity, an indicator of apoptosis, after 8 and 24 h. Antioxidant treatment markedly reduced TBHP-stimulated caspase 3/7 activity, PGE2 release, and IL-6 release. tert-Butylhydroperoxide 140-144 interleukin 6 Homo sapiens 196-200 32542535-7 2020 TBHP-stimulated IL-6 release was blocked by PD169316 but unaltered by indomethacin. tert-Butylhydroperoxide 0-4 interleukin 6 Homo sapiens 16-20 32542535-8 2020 These data suggest that TBHP-stimulated IL-6 release and caspase 3/7 activation were independent of PGE2 yet were interrupted by treatments with known antioxidant properties, providing new insight into relationships between PGE2, IL-6, and apoptosis under conditions of chemically induced cellular oxidation. tert-Butylhydroperoxide 24-28 interleukin 6 Homo sapiens 40-44 32542535-8 2020 These data suggest that TBHP-stimulated IL-6 release and caspase 3/7 activation were independent of PGE2 yet were interrupted by treatments with known antioxidant properties, providing new insight into relationships between PGE2, IL-6, and apoptosis under conditions of chemically induced cellular oxidation. tert-Butylhydroperoxide 24-28 interleukin 6 Homo sapiens 230-234