PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7545698-4 1995 Both prednisolone and GH alleviated the hypoglycemia, concomitantly with increases in IGF-I, IGFBP-3, and ALS levels. Prednisolone 5-17 insulin like growth factor 1 Homo sapiens 86-91 23038624-0 2013 Prednisolone reduces the ability of serum to activate the IGF1 receptor in vitro without affecting circulating total or free IGF1. Prednisolone 0-12 insulin like growth factor 1 Homo sapiens 58-62 23038624-5 2013 RESULTS: Prednisolone treatment reduced IGF1 bioactivity by 12.6% from 2.22+-0.18 to 1.94+-0.15 mug/l (P=0.01) compared with placebo. Prednisolone 9-21 insulin like growth factor 1 Homo sapiens 40-44 11509866-4 2001 RESULTS: IGF-I levels increased by 99% during GH administration and 67% during co-administration of GH and prednisolone (p < 0.0005), whereas no significant change was seen during prednisolone alone. Prednisolone 107-119 insulin like growth factor 1 Homo sapiens 9-14 16079165-10 2006 Serum IGF1 was increased in patients with v without prednisolone, indicating IGF1 resistance (mean (SEM): 221 (23) v 122 (14) microg/l, p<0.001). Prednisolone 52-64 insulin like growth factor 1 Homo sapiens 6-10 16079165-11 2006 Adalimumab treatment decreased the raised IGF1 levels in patients with prednisolone, so that after 12 weeks of treatment they reached the level of patients without prednisolone. Prednisolone 71-83 insulin like growth factor 1 Homo sapiens 42-46 11922563-0 2002 Low free and total insulinlike growth factor I (IGF-I) and IGF binding protein-3 levels in chronic inflammatory bowel disease: partial normalization during prednisolone treatment. Prednisolone 156-168 insulin like growth factor 1 Homo sapiens 19-46 11922563-0 2002 Low free and total insulinlike growth factor I (IGF-I) and IGF binding protein-3 levels in chronic inflammatory bowel disease: partial normalization during prednisolone treatment. Prednisolone 156-168 insulin like growth factor 1 Homo sapiens 48-53 11922563-10 2002 CONCLUSIONS: Marked changes in serum total and free IGF-I and IGFBPs were demonstrated in patients with severe exacerbation of CIBD without complete normalization during high dose prednisolone treatment and tapering. Prednisolone 180-192 insulin like growth factor 1 Homo sapiens 52-57 2278223-0 1990 Insulin-like growth factor-I in prednisolone-treated children. Prednisolone 32-44 insulin like growth factor 1 Homo sapiens 0-28 2278223-4 1990 A significant increase in plasma IGF-I concentrations was noted during long-term (more than 10 days) prednisolone therapy (P less than 0.001), but not found shortly after prednisolone administration. Prednisolone 101-113 insulin like growth factor 1 Homo sapiens 33-38 28945869-7 2017 Results: Prednisolone increased IGF-I concentrations and bioactive IGF in serum (P <= 0.001) but not in SBF, which, compared with serum, contained less bioactive IGF (~28%) after prednisolone (P < 0.05). Prednisolone 9-21 insulin like growth factor 1 Homo sapiens 32-37 31159802-2 2019 Anti-inflammatory treatment with prednisolone or infliximab ameliorates symptoms and increases circulating IGF-I, but prednisolone induces catabolism, whereas infliximab may promote protein synthesis. Prednisolone 33-45 insulin like growth factor 1 Homo sapiens 107-112 31159802-11 2019 RESULTS: Following seven days of prednisolone treatment, total and bioactive IGF-I were increased (p < 0.001 and p < 0.05, respectively). Prednisolone 33-45 insulin like growth factor 1 Homo sapiens 77-82 31159802-15 2019 CONCLUSION: IGF-I and IGFBP-4 concentrations were markedly altered in patients with IBD and near-normalized with disease remission following treatment with prednisolone or infliximab. Prednisolone 156-168 insulin like growth factor 1 Homo sapiens 12-17 28945869-12 2017 Finally, prednisolone suppressed post-IGF-IR signaling pathways at the level of insulin receptor substrate 1 (P < 0.05) but did not change skeletal muscle IGF-IR, IGF-I, or STC2 messenger RNA. Prednisolone 9-21 insulin like growth factor 1 Homo sapiens 38-43 28945869-13 2017 Conclusion: Prednisolone increased IGF-I concentrations and IGF bioactivity in serum but not in tissue fluid. Prednisolone 12-24 insulin like growth factor 1 Homo sapiens 35-40 28688245-6 2017 RESULTS: Evening prednisolone suppressed 24hour GH secretion (P=0.016), overnight GH secretion (P=0.023) and IGF-I (P=0.024) when compared to morning prednisolone, but not when compared to run-in. Prednisolone 17-29 insulin like growth factor 1 Homo sapiens 109-114