PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12388656-5 2002 The slope of Schild plot from the resiniferatoxin efferent studies deviated from unity (~0.6), suggesting complex interactions at VR1 binding site(s). resiniferatoxin 34-49 transient receptor potential cation channel subfamily V member 1 Cavia porcellus 130-133 16627674-7 2006 However, they potentiated citric acid- and resiniferatoxin-induced cough, an effect that was completely prevented by the TRPV1 receptor antagonist capsazepine. resiniferatoxin 43-58 transient receptor potential cation channel subfamily V member 1 Cavia porcellus 121-126 12243775-4 2002 Olvanil and resiniferatoxin were also effective agonists (EC(50) values of 0.0087 +/- 0.0035 micro M and 0.067 +/- 0.014 micro M, respectively), but 12-phenylacetate 13-acetate 20-homovanillate (PPAHV) and anandamide showed little agonist activity up to 10 micro M. As with human and rat VR1, guinea pig VR1 was also activated by pH below 6.0 and by noxious heat (>42 degrees C). resiniferatoxin 12-27 transient receptor potential cation channel subfamily V member 1 Cavia porcellus 304-307 19049892-4 2009 Aerosolized resiniferatoxin (RTX, 0.5 microM) and hypertonic saline (7%) produced a cough response dependent and independent of TRPV1 activation, respectively. resiniferatoxin 12-27 transient receptor potential cation channel subfamily V member 1 Cavia porcellus 128-133