PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34030210-8	2021	In vitro, apigenin behaved as a positive allosteric modulator (PAM) to increase the efficacy (stimulation of [35 S] GTPgammaS binding) of the 5-HT1A receptor agonist 8-OH-DPAT.	Guanosine 5'-O-(3-Thiotriphosphate)	116-125	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	142-157	
16220659-2	2005	Under this condition, a remarkable decrease in [35S]GTPgammaS binding to membranes from the prefrontal cortex, amygdala and hypothalamus of restrained-stress mice stimulated by the selective 5-HT1A receptor agonist 5-carboxamidotriptamine (5-CT) was clearly observed, whereas a significant increase in [35S]GTPgammaS binding stimulated by the 5-HT1A receptor agonist was clearly observed in the dorsal raphe nuclei (DRN) of restrained-stress mice.	Guanosine 5'-O-(3-Thiotriphosphate)	52-61	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	191-206	
16220659-2	2005	Under this condition, a remarkable decrease in [35S]GTPgammaS binding to membranes from the prefrontal cortex, amygdala and hypothalamus of restrained-stress mice stimulated by the selective 5-HT1A receptor agonist 5-carboxamidotriptamine (5-CT) was clearly observed, whereas a significant increase in [35S]GTPgammaS binding stimulated by the 5-HT1A receptor agonist was clearly observed in the dorsal raphe nuclei (DRN) of restrained-stress mice.	Guanosine 5'-O-(3-Thiotriphosphate)	52-61	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	343-358	
17336942-2	2007	METHODS: 5-HT1A receptor function, at the level of receptor-G protein interaction, was assessed with quantitative autoradiography of [35S]GTPgammaS binding stimulated by the 5-HT1A receptor agonist 8-OH-DPAT.	Guanosine 5'-O-(3-Thiotriphosphate)	138-147	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	9-24	
17336942-2	2007	METHODS: 5-HT1A receptor function, at the level of receptor-G protein interaction, was assessed with quantitative autoradiography of [35S]GTPgammaS binding stimulated by the 5-HT1A receptor agonist 8-OH-DPAT.	Guanosine 5'-O-(3-Thiotriphosphate)	138-147	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	174-189	
16219031-5	2005	In parallel, the 5-HT 1A autoreceptor-mediated [35S]GTP-gamma-S binding induced by 5-carboxamidotryptamine onto the DRN in brainstem sections was significantly decreased in GR 205171-treated mice.	Guanosine 5'-O-(3-Thiotriphosphate)	52-63	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	17-24	
23168115-9	2013	Further, 5-HT1A autoreceptor desensitization was evidenced by electrophysiological studies, GTP-gamma-S coupling to 5-HT1A autoreceptor and a lower hypothermic response to 5-HT1A activation.	Guanosine 5'-O-(3-Thiotriphosphate)	92-103	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	9-15	
23505009-4	2013	Four weeks of voluntary wheel running resulted in hippocampal subregion-specific changes in 5-HT1A receptor binding sites and function, as measured by autoradiography of [(3) H] 8-hydroxy-2-(di-n-propylamino)tetralin binding and agonist-stimulated binding of [(35) S]GTPgammaS to G proteins, respectively.	Guanosine 5'-O-(3-Thiotriphosphate)	267-276	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	92-107	
31823197-3	2020	The activity of 5-HT1A receptors was assessed by (+)-8-OH-DPAT-induced hypothermia and [35S]GTPgammaS binding autoradiography.	Guanosine 5'-O-(3-Thiotriphosphate)	87-101	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	16-22	
23168115-9	2013	Further, 5-HT1A autoreceptor desensitization was evidenced by electrophysiological studies, GTP-gamma-S coupling to 5-HT1A autoreceptor and a lower hypothermic response to 5-HT1A activation.	Guanosine 5'-O-(3-Thiotriphosphate)	92-103	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	116-122	
23168115-9	2013	Further, 5-HT1A autoreceptor desensitization was evidenced by electrophysiological studies, GTP-gamma-S coupling to 5-HT1A autoreceptor and a lower hypothermic response to 5-HT1A activation.	Guanosine 5'-O-(3-Thiotriphosphate)	92-103	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	116-122	
22521807-6	2012	This early ethanol exposure enhanced 5-HT(1A) autoreceptor-mediated [(35)S]GTP-gamma-S binding in the dorsal raphe nucleus and reduced CB1 receptor-mediated G protein coupling in both the striatum and the globus pallidus at adult age.	Guanosine 5'-O-(3-Thiotriphosphate)	75-86	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	37-44	
22575584-4	2013	We examined the effect of mild handling stress on 5-HT(1A) receptor function, as measured by 8-OH-DPAT stimulated [(35)S]GTPgammaS binding, in BDNF(+/-) mice and mice with a forebrain-specific reduction in BDNF (embryonic BDNF inducible knockout mice).	Guanosine 5'-O-(3-Thiotriphosphate)	121-130	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	50-67