PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10590233-0 1999 Inhibition of O(6)-methylguanine-DNA methyltransferase increases azoxymethane-induced colonic tumors in rats. Azoxymethane 65-77 O-6-methylguanine-DNA methyltransferase Rattus norvegicus 14-54 24140386-0 2013 Repair and removal of azoxymethane-induced O6-methylguanine in rat colon by O6-methylguanine DNA methyltransferase and apoptosis. Azoxymethane 22-34 O-6-methylguanine-DNA methyltransferase Rattus norvegicus 76-114 24140386-4 2013 In rats given AOM (10 mg/kg), the formation of O(6)meG occurs within 2 h of exposure, accompanied by rapid depletion of MGMT activity and followed by the induction of an acute apoptotic response that peaks at 6-8 h. MGMT repair and apoptosis are dependent on AOM dose and O(6)meG load. Azoxymethane 14-17 O-6-methylguanine-DNA methyltransferase Rattus norvegicus 120-124 24140386-4 2013 In rats given AOM (10 mg/kg), the formation of O(6)meG occurs within 2 h of exposure, accompanied by rapid depletion of MGMT activity and followed by the induction of an acute apoptotic response that peaks at 6-8 h. MGMT repair and apoptosis are dependent on AOM dose and O(6)meG load. Azoxymethane 14-17 O-6-methylguanine-DNA methyltransferase Rattus norvegicus 216-220 24140386-4 2013 In rats given AOM (10 mg/kg), the formation of O(6)meG occurs within 2 h of exposure, accompanied by rapid depletion of MGMT activity and followed by the induction of an acute apoptotic response that peaks at 6-8 h. MGMT repair and apoptosis are dependent on AOM dose and O(6)meG load. Azoxymethane 259-262 O-6-methylguanine-DNA methyltransferase Rattus norvegicus 216-220 24140386-6 2013 AOM, 10 mg/kg, overwhelms MGMT repair for about 96 h and renewed MGMT activity is only observed once O(6)meG is no longer detectable. Azoxymethane 0-3 O-6-methylguanine-DNA methyltransferase Rattus norvegicus 26-30 24140386-6 2013 AOM, 10 mg/kg, overwhelms MGMT repair for about 96 h and renewed MGMT activity is only observed once O(6)meG is no longer detectable. Azoxymethane 0-3 O-6-methylguanine-DNA methyltransferase Rattus norvegicus 65-69 16886601-2 2006 The purpose of this study was to investigate the association between the mRNA expression level of the Mgmt gene and mutation of the beta-catenin gene in rat colon tumors induced by azoxymethane (AOM) plus dextran sulfate sodium (DSS). Azoxymethane 181-193 O-6-methylguanine-DNA methyltransferase Rattus norvegicus 102-106 16886601-2 2006 The purpose of this study was to investigate the association between the mRNA expression level of the Mgmt gene and mutation of the beta-catenin gene in rat colon tumors induced by azoxymethane (AOM) plus dextran sulfate sodium (DSS). Azoxymethane 195-198 O-6-methylguanine-DNA methyltransferase Rattus norvegicus 102-106