PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25212605-1 2014 PURPOSE: We previously showed that EGF receptor (EGFR) promotes tumorigenesis in the azoxymethane/dextran sulfate sodium (AOM/DSS) model, whereas vitamin D suppresses tumorigenesis. Azoxymethane 85-97 epidermal growth factor receptor Mus musculus 35-47 30973663-9 2019 Moreover, when the colorectum of azoxymethane-treated rats was observed using a thin fluorescent endoscope with AF-EGFR-Ab, all 10 small colorectal adenomas (<=3 mm) were detected with a clear fluorescence signal. Azoxymethane 33-45 epidermal growth factor receptor Mus musculus 115-119 28884622-2 2017 OBJECTIVE: To test whether 3-dimensional (3-D) noninvasive in vivo NIRF imaging can detect effects of epidermal growth factor receptor (EGFR) inhibitor on both polypoid and flat tumor load in azoxymethane (AOM)-induced colon tumors or tumors in ApcMin/+ mice. Azoxymethane 192-204 epidermal growth factor receptor Mus musculus 102-134 28884622-2 2017 OBJECTIVE: To test whether 3-dimensional (3-D) noninvasive in vivo NIRF imaging can detect effects of epidermal growth factor receptor (EGFR) inhibitor on both polypoid and flat tumor load in azoxymethane (AOM)-induced colon tumors or tumors in ApcMin/+ mice. Azoxymethane 192-204 epidermal growth factor receptor Mus musculus 136-140 25521828-7 2015 The azoxymethane (AOM)-induced colon carcinogenesis model in Erbin(DeltaC) (/) (DeltaC) mice, with the PDZ domain of Erbin deleted, demonstrated that the PDZ domain of Erbin and its regulation of EGFR signalling are necessary for the tumourigenesis and tumour growth of CRC. Azoxymethane 4-16 epidermal growth factor receptor Mus musculus 196-200 25521828-7 2015 The azoxymethane (AOM)-induced colon carcinogenesis model in Erbin(DeltaC) (/) (DeltaC) mice, with the PDZ domain of Erbin deleted, demonstrated that the PDZ domain of Erbin and its regulation of EGFR signalling are necessary for the tumourigenesis and tumour growth of CRC. Azoxymethane 18-21 epidermal growth factor receptor Mus musculus 196-200 26463023-2 2015 METHODS: Mice with EGFR gene defects in macrophages (Egfr(fl/fl) LysM-Cre) and with EGFR gene expression in macrophages (LysM-Cre) (control group) were treated with azoxymethane (AOM) to establish colorectal tumor models. Azoxymethane 165-177 epidermal growth factor receptor Mus musculus 19-23 25803810-2 2015 Its up-regulation is also important for promotion of the stage of colorectal carcinogenesis in vivo in human NEU3 transgenic mice treated with azoxymethane for the induction of aberrant crypt foci in the colon mucosa, accompanied by enhanced phosphorylation of EGF receptor (EGFR). Azoxymethane 143-155 epidermal growth factor receptor Mus musculus 261-273 25803810-2 2015 Its up-regulation is also important for promotion of the stage of colorectal carcinogenesis in vivo in human NEU3 transgenic mice treated with azoxymethane for the induction of aberrant crypt foci in the colon mucosa, accompanied by enhanced phosphorylation of EGF receptor (EGFR). Azoxymethane 143-155 epidermal growth factor receptor Mus musculus 275-279 25212605-1 2014 PURPOSE: We previously showed that EGF receptor (EGFR) promotes tumorigenesis in the azoxymethane/dextran sulfate sodium (AOM/DSS) model, whereas vitamin D suppresses tumorigenesis. Azoxymethane 85-97 epidermal growth factor receptor Mus musculus 49-53 25212605-1 2014 PURPOSE: We previously showed that EGF receptor (EGFR) promotes tumorigenesis in the azoxymethane/dextran sulfate sodium (AOM/DSS) model, whereas vitamin D suppresses tumorigenesis. Azoxymethane 122-125 epidermal growth factor receptor Mus musculus 35-47 25212605-1 2014 PURPOSE: We previously showed that EGF receptor (EGFR) promotes tumorigenesis in the azoxymethane/dextran sulfate sodium (AOM/DSS) model, whereas vitamin D suppresses tumorigenesis. Azoxymethane 122-125 epidermal growth factor receptor Mus musculus 49-53 19903783-0 2009 Epidermal growth factor receptor is required for colonic tumor promotion by dietary fat in the azoxymethane/dextran sulfate sodium model: roles of transforming growth factor-{alpha} and PTGS2. Azoxymethane 95-107 epidermal growth factor receptor Mus musculus 0-32 21653642-8 2011 These miRNAs were downregulated in azoxymethane and inflammation-associated colonic tumors from Egfr(wt) mice but upregulated in Egfr(wa2) tumors. Azoxymethane 35-47 epidermal growth factor receptor Mus musculus 96-100 19903783-4 2009 Although we showed that epidermal growth factor receptors (EGFR) controlled azoxymethane tumorigenesis in standard fat conditions, the role of EGFR in tumor promotion by high dietary fat has not been examined. Azoxymethane 76-88 epidermal growth factor receptor Mus musculus 59-63 17234795-0 2007 Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis. Azoxymethane 95-107 epidermal growth factor receptor Mus musculus 0-32 17234795-4 2007 In the current study, we used a specific EGFR antagonist, gefitinib, to investigate this role of the receptor in azoxymethane colonic premalignancy. Azoxymethane 113-125 epidermal growth factor receptor Mus musculus 41-45 17234795-10 2007 Azoxymethane significantly induced pro-transforming growth factor-alpha (6.4+/-1.3-fold) and increased phospho-(active) EGFR (5.9+/-1.1-fold), phospho-(active) ErbB2 (2.3+/-0.2-fold), and phospho-(active) extracellular signal-regulated kinase (3.3+/-0.4-fold) in premalignant colonocytes. Azoxymethane 0-12 epidermal growth factor receptor Mus musculus 120-124