PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23027128-2 2013 Disruption of Ptk6 decreases azoxymethane-induced colon tumorigenesis in mice by preventing signal transducer and activator of transcription 3 activation. Azoxymethane 29-41 signal transducer and activator of transcription 3 Mus musculus 92-142 25713055-5 2015 We report that intestinally targeted transgenic 15-LOX-1 expression in mice inhibited azoxymethane- and dextran sodium sulfate-induced CAC, IL-6 expression, STAT3 phosphorylation, and IL-6/STAT3 downstream target (Notch3 and MUC1) expression. Azoxymethane 86-98 signal transducer and activator of transcription 3 Mus musculus 189-194 26137415-3 2015 Formation of Azoxymethane/Dextransulfate (AOM/DSS)-induced CRCs was strongly suppressed in STAT3Deltam mice. Azoxymethane 13-25 signal transducer and activator of transcription 3 Mus musculus 91-96 26137415-3 2015 Formation of Azoxymethane/Dextransulfate (AOM/DSS)-induced CRCs was strongly suppressed in STAT3Deltam mice. Azoxymethane 42-45 signal transducer and activator of transcription 3 Mus musculus 91-96 32024285-0 2020 High-Fat Diet Propelled AOM/DSS-Induced Colitis-Associated Colon Cancer Alleviated by Administration of Aster glehni via STAT3 Signaling Pathway. Azoxymethane 24-27 signal transducer and activator of transcription 3 Mus musculus 121-126 21741923-9 2011 Induction of PTK6 increased apoptosis, proliferation, and STAT3 activation in Ptk6+/+ mice injected with azoxymethane. Azoxymethane 105-117 signal transducer and activator of transcription 3 Mus musculus 58-63 21741923-13 2011 CONCLUSIONS: PTK6 promotes STAT3 activation in the colon following injection of the carcinogen azoxymethane and regulates STAT3 activity in mouse colon tumors and in the HCT116 and young adult mouse colon cell lines. Azoxymethane 95-107 signal transducer and activator of transcription 3 Mus musculus 27-32