PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30798535-2 2019 The azoxymethane/interleukin-10 knockout (AOM/Il10-/-) model is a powerful tool for assessing the effects of intestinal microbiota and inflammation on colon tumorigenesis. Azoxymethane 4-16 interleukin 10 Mus musculus 46-50 26218141-5 2015 Starting at 10 weeks of age, wild-type or Il10 mice received 6 weekly intraperitoneal injections of azoxymethane (AOM) or phosphate-buffered saline (PBS) and were started on either a control or a curcumin-supplemented diet. Azoxymethane 100-112 interleukin 10 Mus musculus 42-46 25781343-4 2015 Arthur and colleagues identified a genotoxic island in Escherichia coli NC101 that appeared to be responsible for causing neoplastic lesions in inflammation-induced IL10-/- mice treated with azoxymethane. Azoxymethane 191-203 interleukin 10 Mus musculus 165-169 35378414-9 2022 The administration of 10 mg/kg tetra- and pentahydroxyflavanones to AOM/DSS-treated mice also resulted in decreases of 59.5 and 42.5% in IL-10 levels and 58.1 and 93.9% in PD-1 levels, respectively, in the colon. Azoxymethane 68-71 interleukin 10 Mus musculus 137-142 32591441-8 2020 In further experiments, we found that the levels of IL-10 were elevated in the serum of Azoxymethane (AOM)/Dextran Sodium Sulfate (DSS)-treated AURKAflox/+;VillinCre+ mice. Azoxymethane 88-100 interleukin 10 Mus musculus 52-57 32591441-8 2020 In further experiments, we found that the levels of IL-10 were elevated in the serum of Azoxymethane (AOM)/Dextran Sodium Sulfate (DSS)-treated AURKAflox/+;VillinCre+ mice. Azoxymethane 102-105 interleukin 10 Mus musculus 52-57 30295289-4 2018 However, for the experiment that compared inflammation, invasion, and neoplasia in azoxymethane (AOM)-treated interleukin-10-deficient mice mono-associated with NC101 or NC101[Formula: see text] pks the experimental timing of the replication attempt was longer than that of the original study. Azoxymethane 83-95 interleukin 10 Mus musculus 110-124 30295289-4 2018 However, for the experiment that compared inflammation, invasion, and neoplasia in azoxymethane (AOM)-treated interleukin-10-deficient mice mono-associated with NC101 or NC101[Formula: see text] pks the experimental timing of the replication attempt was longer than that of the original study. Azoxymethane 97-100 interleukin 10 Mus musculus 110-124 35378414-10 2022 CONCLUSION: The inhibitory effects of tetra- and pentahydroxyflavanones on the growth of colon tumors in AOM/DSS-treated mice appear to be associated with decreases in the colon levels of IL-10 and PD-1 through the down-regulated expression of COX-2 and CD8+ T-cell exhaustion by TOX/TOX2 in the tumor microenvironment. Azoxymethane 105-108 interleukin 10 Mus musculus 188-193 32526927-4 2020 Resveratrol treatment in the azoxymethane (AOM) and dextran sodium sulphate (DSS) CRC murine model caused an increase in anti-inflammatory CD4 + FOXP3 + (Tregs) and CD4 + IL10 + cells, a decrease in proinflammatory Th1 and Th17 cells, and attenuated CRC development. Azoxymethane 43-46 interleukin 10 Mus musculus 171-175