PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34307147-2	2021	We previously reported that Nrf2 deficiency enhances the anti-tumorigenic effect of 17beta-estradiol (E2) in an azoxymethane (AOM)/dextran sodium sulfate (DSS) model of colitis-associated cancer (CAC).	Azoxymethane	112-124	nuclear factor, erythroid derived 2, like 2	Mus musculus	28-32	
34307147-2	2021	We previously reported that Nrf2 deficiency enhances the anti-tumorigenic effect of 17beta-estradiol (E2) in an azoxymethane (AOM)/dextran sodium sulfate (DSS) model of colitis-associated cancer (CAC).	Azoxymethane	126-129	nuclear factor, erythroid derived 2, like 2	Mus musculus	28-32	
34307147-6	2021	Based on Western blotting results, PD-L1 expression was reduced in Nrf2 knockout (KO) female and E2-treated male mice when compared with their wild-type counterparts, following AOM/DSS treatment; this supports the association of PD-L1 expression with tumor progression.	Azoxymethane	177-180	nuclear factor, erythroid derived 2, like 2	Mus musculus	67-71	
19138955-4	2008	Azoxymethane/DSS-treated Nrf2 knockout mice had increased incidence, multiplicity, and size of all colorectal tumors, including adenomas, versus treated wild-type (WT) mice, and the proportion of tumors that were adenocarcinoma was much higher in knockout (80%) versus WT (29%) mice.	Azoxymethane	0-12	nuclear factor, erythroid derived 2, like 2	Mus musculus	25-29	
33842405-0	2021	Nuclear Factor Erythroid 2-related Factor 2 Knockout Suppresses the Development of Aggressive Colorectal Cancer Formation Induced by Azoxymethane/Dextran Sulfate Sodium-Treatment in Female Mice.	Azoxymethane	133-145	nuclear factor, erythroid derived 2, like 2	Mus musculus	0-43	
31628914-9	2019	KEY FINDINGS: In the AOM/DSS model of colitis-associated tumorigenesis, Nrf2-/- mice showed a phenotype similar to WT mice, but with significantly more tumors and a much higher percentage of adenocarcinomas.	Azoxymethane	21-24	nuclear factor, erythroid derived 2, like 2	Mus musculus	72-76	
33068552-0	2020	17beta-Estradiol strongly inhibits azoxymethane/dextran sulfate sodium-induced colorectal cancer development in Nrf2 knockout male mice.	Azoxymethane	35-47	nuclear factor, erythroid derived 2, like 2	Mus musculus	112-116	
24024667-0	2014	Luteolin, a bioflavonoid inhibits Azoxymethane-induced colorectal cancer through activation of Nrf2 signaling.	Azoxymethane	34-46	nuclear factor, erythroid derived 2, like 2	Mus musculus	95-99	
25712056-0	2015	Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde.	Azoxymethane	30-42	nuclear factor, erythroid derived 2, like 2	Mus musculus	0-4	
21355597-0	2011	Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2)-mediated antioxidant signaling pathway.	Azoxymethane	60-72	nuclear factor, erythroid derived 2, like 2	Mus musculus	153-157	
21355597-0	2011	Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2)-mediated antioxidant signaling pathway.	Azoxymethane	74-77	nuclear factor, erythroid derived 2, like 2	Mus musculus	129-151	
21355597-0	2011	Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2)-mediated antioxidant signaling pathway.	Azoxymethane	74-77	nuclear factor, erythroid derived 2, like 2	Mus musculus	153-157	
21355597-0	2011	Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2)-mediated antioxidant signaling pathway.	Azoxymethane	60-72	nuclear factor, erythroid derived 2, like 2	Mus musculus	129-151