PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28971779-0 2018 New Ferrocene Compounds as Selective Cyclooxygenase (COX-2) Inhibitors: Design, Synthesis, Cytotoxicity and Enzyme-inhibitory Activity. ferrocene 4-13 prostaglandin-endoperoxide synthase 2 Homo sapiens 53-58 28971779-15 2018 CONCLUSION: A novel group of ferrocene compounds, possessing a methyl sulfonyl COX-2 pharmacophore were synthesized to investigate the effect of different substituents on selectivity and potency of COX-2 inhibitory activity and their cytotoxicity effects. ferrocene 29-38 prostaglandin-endoperoxide synthase 2 Homo sapiens 79-84 28971779-15 2018 CONCLUSION: A novel group of ferrocene compounds, possessing a methyl sulfonyl COX-2 pharmacophore were synthesized to investigate the effect of different substituents on selectivity and potency of COX-2 inhibitory activity and their cytotoxicity effects. ferrocene 29-38 prostaglandin-endoperoxide synthase 2 Homo sapiens 198-203 28971779-16 2018 This study indicates that 1-ferrocenyl-3-amino carbonyl compounds having ferrocene motif and methyl sulfonyl COX-2 pharmacophore is a suitable scaffold to design COX-2 inhibitors and anti-cancer agents. ferrocene 73-82 prostaglandin-endoperoxide synthase 2 Homo sapiens 162-167