PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22019465-0	2011	Searching for the Multi-Target-Directed Ligands against Alzheimer"s disease: discovery of quinoxaline-based hybrid compounds with AChE, H3R and BACE 1 inhibitory activities.	Quinoxalines	90-101	acetylcholinesterase (Cartwright blood group)	Homo sapiens	130-134	
22019465-1	2011	A novel series of quinoxaline derivatives, as Multi-Target-Directed Ligands (MTDLs) for AD treatment, were designed by lending the core structural elements required for H(3)R antagonists and hybridizing BACE 1 inhibitor 1 with AChE inhibitor BYYT-25.	Quinoxalines	18-29	acetylcholinesterase (Cartwright blood group)	Homo sapiens	227-231	
22019465-2	2011	A virtual database consisting of quinoxaline derivatives was first screened on a pharmacophore model of BACE 1 inhibitors, and then filtered by a molecular docking model of AChE.	Quinoxalines	33-44	acetylcholinesterase (Cartwright blood group)	Homo sapiens	173-177	
33991570-3	2021	Herein, we explored the potential inhibitory activities of various pyridine, quinoxaline, and triazine derivatives (3a-k, 6a-j and 11a-h) against AChE and BuChE enzymes by following the modified Ellman"s method.	Quinoxalines	77-88	acetylcholinesterase (Cartwright blood group)	Homo sapiens	146-150