PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15802852-2 2005 The Zn(II) complex showed strong alpha-glucosidase inhibitory activity greater by about eighty times (substrate: maltose) and forty times (substrate: sucrose) compared with acarbose. Sucrose 150-157 sucrase isomaltase (alpha-glucosidase) Mus musculus 33-50 19420711-2 2009 The simultaneous oral administration of the extract at a dose of 1.0 mg/mouse with maltose or sucrose inhibited the postprandial elevation of the plasma glucose and insulin levels and intestinal alpha-glucosidase activities in mice. Sucrose 94-101 sucrase isomaltase (alpha-glucosidase) Mus musculus 195-212 34455958-9 2022 From the in vitro studies, the position and number of the feruloyl substituents on the sucrose core, the aromatic "OH" group, and the diisopropylidene bridges were key determinants of the % inhibition of alpha-glucosidase and alpha-amylase. Sucrose 87-94 sucrase isomaltase (alpha-glucosidase) Mus musculus 204-221 34914943-1 2022 BACKGROUND & AIMS: The sucrase-isomaltase (SI) c.273_274delAG loss-of-function variant is common in Arctic populations and causes congenital sucrase-isomaltase deficiency, an inability to breakdown and absorb sucrose and isomaltose. Sucrose 209-216 sucrase isomaltase (alpha-glucosidase) Mus musculus 23-41 34914943-1 2022 BACKGROUND & AIMS: The sucrase-isomaltase (SI) c.273_274delAG loss-of-function variant is common in Arctic populations and causes congenital sucrase-isomaltase deficiency, an inability to breakdown and absorb sucrose and isomaltose. Sucrose 209-216 sucrase isomaltase (alpha-glucosidase) Mus musculus 43-45 34914943-9 2022 CONCLUSIONS: These results suggest that sucrase-isomaltase constitutes a promising drug target for improvement of metabolic health, and that the health benefits are mediated by reduced dietary sucrose uptake and possibly also by higher levels of circulating acetate. Sucrose 193-200 sucrase isomaltase (alpha-glucosidase) Mus musculus 40-58 32722136-4 2020 The potential as alpha-glucosidase inhibitors of products was evaluated with oral sucrose and lactose tolerance (OSTT and OLTT, respectively) and intestinal sucrose hydrolysis (ISH) tests; the potential as SGLT-1 inhibitors was evaluated using oral glucose tolerance (OGTT), intestinal glucose absorption (IGA), and urinary glucose excretion (UGE) tests. Sucrose 82-89 sucrase isomaltase (alpha-glucosidase) Mus musculus 17-34 32722136-4 2020 The potential as alpha-glucosidase inhibitors of products was evaluated with oral sucrose and lactose tolerance (OSTT and OLTT, respectively) and intestinal sucrose hydrolysis (ISH) tests; the potential as SGLT-1 inhibitors was evaluated using oral glucose tolerance (OGTT), intestinal glucose absorption (IGA), and urinary glucose excretion (UGE) tests. Sucrose 157-164 sucrase isomaltase (alpha-glucosidase) Mus musculus 17-34 29621479-9 2018 In support of this possibility, we reported that acarbose (an alpha-glucosidase inhibitor) prevented sucrose, maltose and Polycose from eliciting CPIR. Sucrose 101-108 sucrase isomaltase (alpha-glucosidase) Mus musculus 62-79 27399232-5 2016 The alpha-glucosidase inhibitory properties of 1 were confirmed in vivo with an oral sucrose tolerance test in normal and hyperglycemic mice (p < 0.05). Sucrose 85-92 sucrase isomaltase (alpha-glucosidase) Mus musculus 4-21