PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31012189-8	2019	Two DNMT1 inhibitors (5-aza-dC and zebularine) suppressed OCT4-induced MDA-MB-231 cell proliferation through Ras/Raf1/ERK inactivation by targeting ISL1, which is the downstream of DNMT1.	pyrimidin-2-one beta-ribofuranoside	35-45	POU class 5 homeobox 1	Homo sapiens	58-62	
30196805-4	2019	First, reduced overall DNA methylation patterns and gene-specific DNA methylation levels at the promoter regions of pluripotency genes (octamer-binding transcription factor 4 (Oct4), SRY (sex determining region Y)-box 2 (Sox2) and Nanog) were found in zebularine-treated cumulus cells.	pyrimidin-2-one beta-ribofuranoside	252-262	POU class 5 homeobox 1	Homo sapiens	136-174	
30196805-7	2019	Moreover, the abundance of Oct4 and Sox2 mRNA was significantly increased during the preimplantation stages after zebularine treatment (P<0.05).	pyrimidin-2-one beta-ribofuranoside	114-124	POU class 5 homeobox 1	Homo sapiens	27-31	
23790013-5	2013	The treatment of fibroblasts with Zebularine or Zebularine plus Scriptaid increased histone acetylation of histone 3 lysine 9 (H3K9), but decreased the level of DNA methylation of Oct-4 and Sox-2 promoter regions.	pyrimidin-2-one beta-ribofuranoside	34-44	POU class 5 homeobox 1	Homo sapiens	180-185	
23790013-5	2013	The treatment of fibroblasts with Zebularine or Zebularine plus Scriptaid increased histone acetylation of histone 3 lysine 9 (H3K9), but decreased the level of DNA methylation of Oct-4 and Sox-2 promoter regions.	pyrimidin-2-one beta-ribofuranoside	48-58	POU class 5 homeobox 1	Homo sapiens	180-185