PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21489792-6 2011 In particular, compound 17 with the aromatic piperazinosulfonyl substituent showed the most potent (IC(50)=1.30 muM) and selective (over other kinases such as p38alpha, p38beta, JNK1, JNK2, JNK3, and IKK-1) inhibitory activity against IKK-2. aromatic piperazinosulfonyl 36-63 latexin Homo sapiens 112-115