PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 149141-5 1978 Plasma renin activity was not significantly increased after 4 days of treatment but had risen to the normal range by the termination of aminoglutethimide therapy. Aminoglutethimide 136-153 renin Homo sapiens 7-12 149141-10 1978 The observation that chronic administration of aminoglutethimide lowered blood pressure in these patients and elevated their plasma renin activity to the normal range without decreasing production of the adrenal steroids, deoxycorticosterone, 18-hydroxydeoxycorticosterone, and 16beta-hydroxydehydroepiandrosterone, makes it unlikely that these steroids are responsible either for the decreased renin or the elevated blood pressure in patients with low renin essential hypertension. Aminoglutethimide 47-64 renin Homo sapiens 132-137 149141-10 1978 The observation that chronic administration of aminoglutethimide lowered blood pressure in these patients and elevated their plasma renin activity to the normal range without decreasing production of the adrenal steroids, deoxycorticosterone, 18-hydroxydeoxycorticosterone, and 16beta-hydroxydehydroepiandrosterone, makes it unlikely that these steroids are responsible either for the decreased renin or the elevated blood pressure in patients with low renin essential hypertension. Aminoglutethimide 47-64 renin Homo sapiens 395-400 149141-10 1978 The observation that chronic administration of aminoglutethimide lowered blood pressure in these patients and elevated their plasma renin activity to the normal range without decreasing production of the adrenal steroids, deoxycorticosterone, 18-hydroxydeoxycorticosterone, and 16beta-hydroxydehydroepiandrosterone, makes it unlikely that these steroids are responsible either for the decreased renin or the elevated blood pressure in patients with low renin essential hypertension. Aminoglutethimide 47-64 renin Homo sapiens 395-400 149141-0 1978 Effect of aminoglutethimide on blood pressure and steroid secretion in patients with low renin essential hypertension. Aminoglutethimide 10-27 renin Homo sapiens 89-94