PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30113702-1 2018 We previously showed that (+)-tramadol is metabolized in dog liver to (+)-M1 exclusively by CYP2D15 and to (+)-M2 by multiple CYPs, but primarily CYP2B11. Tramadol 26-38 cytochrome P450 2B11 Canis lupus familiaris 146-153