PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25584932-4	2015	Black and Hispanic populations are known to have a higher prevalence of cardiovascular risk factors and disease, and a substantial proportion of black and Hispanic individuals possess genotypes of the cytochrome P450 (CYP) 2C9 enzyme involved in the metabolism of many NSAIDs and the CYP2D6 enzyme involved in metabolism of the dual opioid agonist/norepinephrine-serotonin reuptake inhibitor tramadol.	Tramadol	392-400	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	201-226	
34246203-4	2021	The aims of the present study are to assess the possible association of CYP2D6 and CYP2C9 polymorphisms with the efficacy and safety of tramadol and ketorolac in postoperative pain.	Tramadol	136-144	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	83-89	
34246203-15	2021	CONCLUSIONS: CYP2D6 and CYP2C9 can predict analgesic effectiveness of tramadol and ketorolac.	Tramadol	70-78	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	24-30