PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17120754-2 2006 We aimed to observe the effects of morphine, fentanyl and tramadol on NF-kappa B and IL-2 from both laboratory and clinical perspective. Tramadol 58-66 interleukin 2 Homo sapiens 85-89 16171665-1 2005 STUDY OBJECTIVE: To investigate the effect of tramadol on the production of serum interleukin (IL) 6, IL-10, and IL-2 and soluble (s) IL-2 receptor (R), thereby evaluating its effects on the proinflammatory and anti-inflammatory responses and immune function in cancer patients undergoing conventional pulmonary lobectomy. Tramadol 46-54 interleukin 2 Homo sapiens 113-117 16171665-1 2005 STUDY OBJECTIVE: To investigate the effect of tramadol on the production of serum interleukin (IL) 6, IL-10, and IL-2 and soluble (s) IL-2 receptor (R), thereby evaluating its effects on the proinflammatory and anti-inflammatory responses and immune function in cancer patients undergoing conventional pulmonary lobectomy. Tramadol 46-54 interleukin 2 Homo sapiens 134-138 16171665-16 2005 As tramadol was associated with increased IL-2 and delayed enhancement of sIL-2R in our study, it may attenuate to some extent an impaired immune response in pulmonary lobectomy. Tramadol 3-11 interleukin 2 Homo sapiens 42-46 33385878-7 2021 Besides, tramadol activates natural killer (NK) and T-cells and enhances IL-2 secretion, which produce immune-enhancing effect against SARS-CoV-2. Tramadol 9-17 interleukin 2 Homo sapiens 73-77