PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19275775-6 2009 The exaggerated response to tramadol in SERT-/- mice was blocked by pretreatment with the 5-HT1A antagonist WAY 100635. Tramadol 28-36 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 90-96 16832657-0 2006 Differential role of 5-HT1A and 5-HT1B receptors on the antinociceptive and antidepressant effect of tramadol in mice. Tramadol 101-109 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 21-38 16832657-2 2006 OBJECTIVES: The present study was undertaken to evaluate the potential role of 5-HT1A and 5-HT1B receptors on the analgesic and antidepressant-like effect of tramadol. Tramadol 158-166 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 79-96 16832657-6 2006 CONCLUSIONS: These findings suggest that 5-HT1A receptors modulate the analgesic and the antidepressant-like effects of tramadol in differing ways. Tramadol 120-128 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 41-47 16832657-8 2006 In contrast, the 5-HT1A receptors located in the forebrain may be responsible for the blockade of the antidepressant-like effect of tramadol. Tramadol 132-140 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 17-23 15777775-0 2005 Role of 5-HT1A and 5-HT1B receptors in the antinociceptive effect of tramadol. Tramadol 69-77 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 8-25 15777775-6 2005 These results account for involvement of the somatodendritic 5-HT1A receptors in the analgesic effect of tramadol and support the supraspinal interaction of serotonin and the opioid system in the regulation of pain. Tramadol 105-113 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 61-67