PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21515050-1 2011 SAR exploration at C-6 and C-8 positions of the tricyclic sulfone series was carried out. tricyclic sulfone 48-65 complement component 6 Mus musculus 19-22 21515050-3 2011 Selective combination of C-6 and C-8 modification resulted in new tricyclic sulfone analogs with efficacy in in vivo mouse Abeta(40) lowering model. tricyclic sulfone 66-83 complement component 6 Mus musculus 25-28