PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10999957-1 2000 We previously demonstrated differential interactions of the methoxychlor metabolite 2,2-bis(p-hydroxyphenyl)-1,1, 1-trichloroethane (HPTE) with estrogen receptor alpha (ERalpha), ERbeta, and the androgen receptor (AR). Methoxychlor 60-72 estrogen receptor 2 Homo sapiens 179-185 10999957-2 2000 In this study, we characterize the ERalpha, ERbeta, and AR activity of structurally related methoxychlor metabolites. Methoxychlor 92-104 estrogen receptor 2 Homo sapiens 44-50 10999957-5 2000 The monohydroxy analog of methoxychlor, as well as monohydroxy and dihydroxy analogs of 2, 2-bis(p-hydroxyphenyl)-1,1-dichloroethylene, had ERalpha agonist activity and ERbeta and AR antagonist activity similar to HPTE. Methoxychlor 26-38 estrogen receptor 2 Homo sapiens 169-175