PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15256468-5	2004	In vitro, both verapamil and its derivative inhibited leukotriene C4 transport by MRP1-enriched membrane vesicles in a competitive manner, with a K(i) of 48.6 microm for verapamil and 5.5 microm for NMeOHI(2,) and stimulated reduced glutathione (GSH) transport 3-fold and 9-fold, respectively.	Glutathione	233-244	ATP-dependent translocase ABCB1	Mesocricetus auratus	82-86	
15256468-0	2004	Verapamil and its derivative trigger apoptosis through glutathione extrusion by multidrug resistance protein MRP1.	Glutathione	55-66	ATP-dependent translocase ABCB1	Mesocricetus auratus	109-113	
15256468-5	2004	In vitro, both verapamil and its derivative inhibited leukotriene C4 transport by MRP1-enriched membrane vesicles in a competitive manner, with a K(i) of 48.6 microm for verapamil and 5.5 microm for NMeOHI(2,) and stimulated reduced glutathione (GSH) transport 3-fold and 9-fold, respectively.	Glutathione	246-249	ATP-dependent translocase ABCB1	Mesocricetus auratus	82-86	
15256468-6	2004	Treatment of MRP1-expressing cells with either verapamil or the derivative quickly depleted intracellular GSH content with a strong decrease occurring in the first hour of treatment, which preceded cell death beginning at 8-16 h. Furthermore, addition of GSH to the media efficiently prevented cell death.	Glutathione	106-109	ATP-dependent translocase ABCB1	Mesocricetus auratus	13-17	
15256468-6	2004	Treatment of MRP1-expressing cells with either verapamil or the derivative quickly depleted intracellular GSH content with a strong decrease occurring in the first hour of treatment, which preceded cell death beginning at 8-16 h. Furthermore, addition of GSH to the media efficiently prevented cell death.	Glutathione	255-258	ATP-dependent translocase ABCB1	Mesocricetus auratus	13-17	
15256468-7	2004	Therefore, verapamil and its derivative trigger apoptosis through stimulation of GSH extrusion mediated by MRP1.	Glutathione	81-84	ATP-dependent translocase ABCB1	Mesocricetus auratus	107-111