PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18848961-3	2009	In this work we show that in FaO rat hepatoma cells inhibition of the epidermal growth factor receptor (EGFR) with the tyrphostin AG1478 enhances TGF-beta-induced cell death, coincident with an elevated increase in ROS production and GSH depletion.	Glutathione	234-237	epidermal growth factor receptor	Rattus norvegicus	70-102	
18848961-3	2009	In this work we show that in FaO rat hepatoma cells inhibition of the epidermal growth factor receptor (EGFR) with the tyrphostin AG1478 enhances TGF-beta-induced cell death, coincident with an elevated increase in ROS production and GSH depletion.	Glutathione	234-237	epidermal growth factor receptor	Rattus norvegicus	104-108	
12874275-0	2003	Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43: role of glutathione and tyrosine phosphatases.	Glutathione	134-145	epidermal growth factor receptor	Rattus norvegicus	0-32	
12874275-6	2003	The mere depletion of GSH by application of diethyl maleate EGFR-dependently activated ERK and Akt, thus mimicking BQ effects.	Glutathione	22-25	epidermal growth factor receptor	Rattus norvegicus	60-64	
7798194-5	1994	When expressed as a glutathione S-transferase fusion protein, this amino-terminal domain binds to autophosphorylated EGF receptor, as well as HER2/neu and TrkA receptors.	Glutathione	20-31	epidermal growth factor receptor	Rattus norvegicus	117-129	
12874275-8	2003	In summary, EGFR-dependent signaling was mediated by protein-tyrosine phosphatase inactivation (menadione), GSH depletion (BQ), and redox-cycling (DMNQ), funneling into the same signaling pathway.	Glutathione	108-111	epidermal growth factor receptor	Rattus norvegicus	12-16	
10666084-4	2000	The stretch rapidly (within 2 min) induced association of tyrosine-phosphorylated EGFR with adaptor proteins (Shc/Grb2) as revealed by coprecipitation with glutathione-S-transferase-Grb2 fusion protein coupled with immunoblotting with anti-phosphotyrosine, anti-EGFR, and anti-Shc antibodies.	Glutathione	156-167	epidermal growth factor receptor	Rattus norvegicus	82-86	
32971455-6	2020	It was found that 22 potential toxic components screened can affect Th17 cell differentiation, Jak-STAT signaling pathway, glutathione metabolism, and other related pathways by regulating AKT1, IL2, F2, GSR, EGFR and other related targets, which induces oxidative stress, metabolic disorders, cell apoptosis, immune response, and excessive release of inflammatory factors, eventually inducing liver damage in rats.	Glutathione	123-134	epidermal growth factor receptor	Rattus norvegicus	208-212