PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32910833-0 2021 Baicalein inhibits FURIN-MT1-MMP-mediated invasion of ectopic endometrial stromal cells in endometriosis possibly by reducing the secretion of TGFB1. baicalein 0-9 furin (paired basic amino acid cleaving enzyme) Mus musculus 19-24 32910833-10 2021 Exposure to baicalein reduced the extracellular levels of TGFB1 in EcESCs, and the reduced expression of TGFB1, resulting in decreased expression of FURIN in EcESCs, which serves a pivotal role in the transformation of pro-MT1-MMP to activated MT1-MMP. baicalein 12-21 furin (paired basic amino acid cleaving enzyme) Mus musculus 149-154 32910833-11 2021 In the mouse model of EMs, intraperitoneal injection of baicalein inhibited the growth of ectopic lesions, and reduced MT1-MMP, FURIN and TGFB1 expression. baicalein 56-65 furin (paired basic amino acid cleaving enzyme) Mus musculus 128-133 32910833-12 2021 CONCLUSIONS: Baicalein reduced the invasion of EMs, potentially by restricting the FURIN-MT1-MMP-mediated cell invasion of EcESCs maybe through reduction of the autocrine of TGFB1. baicalein 13-22 furin (paired basic amino acid cleaving enzyme) Mus musculus 83-88