PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12125101-1 2002 In an earlier study, we have reported an inhibition of insulin receptor (IR) mRNA levels and insulin binding by aldosterone in U-937 human promonocytic cells. Aldosterone 112-123 insulin receptor Homo sapiens 55-71 12767279-0 2003 Transcriptional inhibition of the human insulin receptor gene by aldosterone. Aldosterone 65-76 insulin receptor Homo sapiens 40-56 12767279-1 2003 In earlier studies, we reported reduced human insulin receptor (hIR) mRNA levels, insulin binding and insulin responsiveness in U-937 human promonocytic cells treated with aldosterone. Aldosterone 172-183 insulin receptor Homo sapiens 46-62 10622410-7 1999 The inhibitory action of aldosterone was not prevented by the simultaneous presence of the protein synthesis inhibitor cycloheximide, suggesting that the reduction of IR gene expression occurs as a direct response to the action of aldosterone. Aldosterone 25-36 insulin receptor Homo sapiens 167-169 10622410-7 1999 The inhibitory action of aldosterone was not prevented by the simultaneous presence of the protein synthesis inhibitor cycloheximide, suggesting that the reduction of IR gene expression occurs as a direct response to the action of aldosterone. Aldosterone 231-242 insulin receptor Homo sapiens 167-169 10622410-10 1999 These results provide the first evidence for an in vitro modulation of human IR expression by aldosterone. Aldosterone 94-105 insulin receptor Homo sapiens 77-79