PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8807826-3 1996 A mutant enzyme (VanA) from vancomycin-resistant Enterococcus faecium has been found to incorporate alpha-hydroxy acids at the terminal site instead of D-Ala; the resulting depsipeptides do not bind vancomycin, yet function in the crosslinking reaction. alpha-hydroxy acids 100-119 Vancomycin Teicoplanin A-type resistance protein VanA / D-alanine--D-alanine ligase Enterococcus faecium 17-21