PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
3589146-0	1987	Albumin as a potential membrane transport barrier for hepatic clearance of diazepam studied by a universal organ clearance approach.	Diazepam	75-83	albumin	Rattus norvegicus	0-7	
34229248-6	2021	Diazepam was selected to illustrate different levels of drug plasma-protein binding by changing the added concentration of human serum albumin.	Diazepam	0-8	albumin	Rattus norvegicus	129-142	
2794052-6	1989	The absence of albumin in the latter increased the unbound fraction of diazepam by almost fivefold; however, in both groups, the ratio of unbound concentrations in brain and blood at equilibrium was equal to unity.	Diazepam	71-79	albumin	Rattus norvegicus	15-22	
3377952-2	1988	The impact of anaesthetic-induced action on enzyme activity and diazepam binding to human serum albumin (HSA) was assessed in protein free and protein containing buffers, respectively.	Diazepam	64-72	albumin	Rattus norvegicus	90-103	
3377952-3	1988	Human serum albumin reduced the elimination of diazepam by 12 and 50% at concentrations of 1 and 10 mg ml-1, respectively.	Diazepam	47-55	albumin	Rattus norvegicus	6-19	
3589146-1	1987	Published data on the effect of albumin binding on hepatic extraction of diazepam in isolated perfused rat livers were analyzed by a simple universal organ clearance approach proposed earlier by this author.	Diazepam	73-81	albumin	Rattus norvegicus	32-39	
6149902-6	1984	However, if the bovine serum albumin was omitted from the perfusate, diazepam uptake in the IPL increased about 10-fold while methadone uptake increased only slightly.	Diazepam	69-77	albumin	Rattus norvegicus	23-36