PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
6320963-2	1984	We investigated whether the inhibition of PRL secretion by the benzodiazepine receptor agonist, diazepam, occurs directly at the pituitary.	Diazepam	96-104	prolactin	Rattus norvegicus	42-45	
1321364-4	1992	Clonazepam (1 and 5 mg/kg) and diazepam (15 mg/kg but not 25 mg/kg) decreased even the TRH-induced PRL levels.	Diazepam	31-39	prolactin	Rattus norvegicus	99-102	
2876582-0	1986	Effect of diazepam and medazepam on prolactin secretion.	Diazepam	10-18	prolactin	Rattus norvegicus	36-45	
2876582-1	1986	Pharmacological studies of the effect of Diazepam and Medazepam on prolactin secretion were carried out on sexually mature male albino rats.	Diazepam	41-49	prolactin	Rattus norvegicus	67-76	
2876582-6	1986	Prolactin secretion decreases after a single intraperitoneal administration of Diazepam in both doses.	Diazepam	79-87	prolactin	Rattus norvegicus	0-9	
6320963-3	1984	At nanomolar concentrations diazepam did not affect PRL secretion, whereas at micromolar concentrations, diazepam dose-dependently inhibited basal and secretagogue-stimulated PRL release from hemipituitary glands and from primary cultures of rat anterior pituitary cells.	Diazepam	105-113	prolactin	Rattus norvegicus	175-178	
6320963-5	1984	Although nanomolar concentrations of diazepam alone did not affect PRL release, they did enhance the PRL inhibitory effect of muscimol, a gamma-amino butyric acid (GABA) receptor agonist.	Diazepam	37-45	prolactin	Rattus norvegicus	101-104	
6320963-7	1984	Since these effects do not appear to occur through an inhibition of the cAMP generating system, diazepam may inhibit PRL release via a cAMP-independent pathway.	Diazepam	96-104	prolactin	Rattus norvegicus	117-120	
6320963-8	1984	We suggest that diazepam inhibits PRL secretion either by enhancing the GABAergic inhibition of PRL release, or by inhibiting, at micromolar concentrations, a benzodiazepine-sensitive Ca2+-calmodulin dependent protein kinase.	Diazepam	16-24	prolactin	Rattus norvegicus	34-37	
6320963-8	1984	We suggest that diazepam inhibits PRL secretion either by enhancing the GABAergic inhibition of PRL release, or by inhibiting, at micromolar concentrations, a benzodiazepine-sensitive Ca2+-calmodulin dependent protein kinase.	Diazepam	16-24	prolactin	Rattus norvegicus	96-99	
6979001-3	1982	The benzodiazepine diazepam blocked stress-induced prolactin release and, when given during the critical period of proestrus, the proestrus surge of prolactin.	Diazepam	19-27	prolactin	Rattus norvegicus	51-60	
6979001-3	1982	The benzodiazepine diazepam blocked stress-induced prolactin release and, when given during the critical period of proestrus, the proestrus surge of prolactin.	Diazepam	19-27	prolactin	Rattus norvegicus	149-158	
6979001-4	1982	Diazepam administration also blunted the release of prolactin induced by dopaminergic receptor blockade following haloperidol, or by serotonergic receptor activation produced by fluoxetine, a serotonergic reuptake inhibitor plus 5-hydroxytryptophan, a serotonin precursor.	Diazepam	0-8	prolactin	Rattus norvegicus	52-61	
6979001-5	1982	Inhibition of prolactin release by benzodiazepine was dose related, and inhibition was still evident after repeated diazepam injection.	Diazepam	116-124	prolactin	Rattus norvegicus	14-23	
6979001-6	1982	The potency of three benzodiazepine analogues to inhibit prolactin release correlated with their potency to displace radiolabeled diazepam binding from brain membrane fractions or to induce other biological responses (clonazepam greater than diazepam greater than chlordiazepoxide).	Diazepam	130-138	prolactin	Rattus norvegicus	57-66	
6979001-6	1982	The potency of three benzodiazepine analogues to inhibit prolactin release correlated with their potency to displace radiolabeled diazepam binding from brain membrane fractions or to induce other biological responses (clonazepam greater than diazepam greater than chlordiazepoxide).	Diazepam	242-250	prolactin	Rattus norvegicus	57-66	
6322044-3	1983	Diazepam reduced the rise in secretion of prolactin during proestrus and the increase in release induced by stress, administration of fluoxetine plus 5-hydroxytryptophan and haloperidol.	Diazepam	0-8	prolactin	Rattus norvegicus	42-51	
6322044-9	1983	In cultures of anterior pituitary cells diazepam enhanced the inhibition of prolactin secretion produced by gamma-aminobutyric acid (GABA) and dopamine.	Diazepam	40-48	prolactin	Rattus norvegicus	76-85