PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18554714-4 2008 We have previously shown that chronic antidepressant treatments increase the binding of a GalR2-preferring ligand, galanin (2-11), to the dorsal raphe nucleus (DRN) of the rat, which, along with the finding that intra-DRN infusion of galanin (2-11) increases the release of serotonin in the hippocampus, suggests that GalR2 signaling might exert antidepressant-like actions by modulating ascending serotonergic outflow. Serotonin 274-283 galanin and GMAP prepropeptide Mus musculus 115-122 20589909-4 2010 Even if similarly distributed, the serotonin neurons in mouse lacked the extensive coexpression of nitric oxide synthase and galanin seen in rat. Serotonin 35-44 galanin and GMAP prepropeptide Mus musculus 125-132 16611095-1 2006 Galanin is a neuropeptide synthesized in many neuronal types including brainstem norepinephrine-producing cells of the locus coeruleus and the serotonin-producing neurons of the dorsal raphe nucleus. Serotonin 143-152 galanin and GMAP prepropeptide Mus musculus 0-7 16611095-2 2006 Galanin inhibits the firing of rodent norepinephrine, serotonin and dopamine neurons and reduces release of these neurotransmitters in forebrain target regions. Serotonin 54-63 galanin and GMAP prepropeptide Mus musculus 0-7 16863269-8 2006 In this context, galanin is of particular interest, since it is co-localised with serotonin in the dorsal raphe nucleus and with noradrenaline in the locus coeruleus, nuclei known to play a major role in affective disorders and in the action of antidepressant drugs. Serotonin 82-91 galanin and GMAP prepropeptide Mus musculus 17-24 16863269-10 2006 Studies in rats have shown that galanin administered intracerebroventricularly is a potent inhibitor of mesencephalic serotonergic neurotransmission, as indicated by a long-lasting reduction in the release of serotonin in the hippocampus. Serotonin 209-218 galanin and GMAP prepropeptide Mus musculus 32-39 16863269-19 2006 On the other hand, stimulation of the GAL2 receptor at the raphe level by local application of the GAL2 receptor agonist galanin (2-11) has been shown to increase serotonin levels in the hippocampus and dorsal raphe. Serotonin 163-172 galanin and GMAP prepropeptide Mus musculus 121-128 16863269-20 2006 These results indicate an important (mainly inhibitory) role of galanin as a regulator of brain serotonin and 5-HT1A receptor-mediated transmission, which may be of potential importance for understanding mood disorders and for the development of antidepressant drugs. Serotonin 96-105 galanin and GMAP prepropeptide Mus musculus 64-71 16219029-4 2005 Infusion of a mixed agonist of galanin receptors types 1 and 2 [galanin (1-29)] into the DR augmented the severity of limbic seizures in both rats and wild-type mice and concurrently reduced serotonin concentration in the DR and hippocampus as measured by immunofluorescence or HPLC. Serotonin 191-200 galanin and GMAP prepropeptide Mus musculus 31-38 16219029-4 2005 Infusion of a mixed agonist of galanin receptors types 1 and 2 [galanin (1-29)] into the DR augmented the severity of limbic seizures in both rats and wild-type mice and concurrently reduced serotonin concentration in the DR and hippocampus as measured by immunofluorescence or HPLC. Serotonin 191-200 galanin and GMAP prepropeptide Mus musculus 64-71 16219029-5 2005 In contrast, injection of the galanin receptor type 2 agonist galanin (2-11) mitigated the severity of seizures in both species and increased serotonin concentration in both areas. Serotonin 142-151 galanin and GMAP prepropeptide Mus musculus 30-37 16219029-5 2005 In contrast, injection of the galanin receptor type 2 agonist galanin (2-11) mitigated the severity of seizures in both species and increased serotonin concentration in both areas. Serotonin 142-151 galanin and GMAP prepropeptide Mus musculus 62-69 16219029-7 2005 Both the proconvulsant activity of galanin (1-29) and seizure suppression by galanin (2-11) were abolished in serotonin-depleted animals. Serotonin 110-119 galanin and GMAP prepropeptide Mus musculus 35-42 16219029-7 2005 Both the proconvulsant activity of galanin (1-29) and seizure suppression by galanin (2-11) were abolished in serotonin-depleted animals. Serotonin 110-119 galanin and GMAP prepropeptide Mus musculus 77-84 12581166-1 2003 Galanin and galanin receptors are widely expressed by neurons in rat brain that either synthesize/release and/or are responsive to, classical transmitters such as gamma-aminobutyric acid, acetylcholine, noradrenaline, histamine, dopamine and serotonin (5-hydroxytryptamine, 5-HT). Serotonin 242-251 galanin and GMAP prepropeptide Mus musculus 0-7 14701907-0 2004 Enhanced hippocampal noradrenaline and serotonin release in galanin-overexpressing mice after repeated forced swimming test. Serotonin 39-48 galanin and GMAP prepropeptide Mus musculus 60-67 12700679-1 2003 The neuropeptide galanin coexists with norepinephrine and serotonin in neural systems mediating emotion. Serotonin 58-67 galanin and GMAP prepropeptide Mus musculus 17-24 12581166-1 2003 Galanin and galanin receptors are widely expressed by neurons in rat brain that either synthesize/release and/or are responsive to, classical transmitters such as gamma-aminobutyric acid, acetylcholine, noradrenaline, histamine, dopamine and serotonin (5-hydroxytryptamine, 5-HT). Serotonin 242-251 galanin and GMAP prepropeptide Mus musculus 12-19 12581166-1 2003 Galanin and galanin receptors are widely expressed by neurons in rat brain that either synthesize/release and/or are responsive to, classical transmitters such as gamma-aminobutyric acid, acetylcholine, noradrenaline, histamine, dopamine and serotonin (5-hydroxytryptamine, 5-HT). Serotonin 253-272 galanin and GMAP prepropeptide Mus musculus 0-7 12581166-1 2003 Galanin and galanin receptors are widely expressed by neurons in rat brain that either synthesize/release and/or are responsive to, classical transmitters such as gamma-aminobutyric acid, acetylcholine, noradrenaline, histamine, dopamine and serotonin (5-hydroxytryptamine, 5-HT). Serotonin 253-272 galanin and GMAP prepropeptide Mus musculus 12-19 12581166-1 2003 Galanin and galanin receptors are widely expressed by neurons in rat brain that either synthesize/release and/or are responsive to, classical transmitters such as gamma-aminobutyric acid, acetylcholine, noradrenaline, histamine, dopamine and serotonin (5-hydroxytryptamine, 5-HT). Serotonin 274-278 galanin and GMAP prepropeptide Mus musculus 0-7 12581166-1 2003 Galanin and galanin receptors are widely expressed by neurons in rat brain that either synthesize/release and/or are responsive to, classical transmitters such as gamma-aminobutyric acid, acetylcholine, noradrenaline, histamine, dopamine and serotonin (5-hydroxytryptamine, 5-HT). Serotonin 274-278 galanin and GMAP prepropeptide Mus musculus 12-19 10422730-8 1999 Finally, galanin is co-localized with classic monoamine transmitters in two central systems, the dorsal raphe serotonin neurons and the locus coeruleus noradrenergic neurons. Serotonin 110-119 galanin and GMAP prepropeptide Mus musculus 9-16 8997601-0 1996 Effects of galanin on 8-OH-DPAT induced decrease in body temperature and brain 5-hydroxytryptamine metabolism in the mouse. Serotonin 79-98 galanin and GMAP prepropeptide Mus musculus 11-18