PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17039513-5	2007	In this study, the ability of a novel platelet GPIIb/IIIa antagonist, a free acid form of roxifiban (XV459), to block platelet activation/aggregation in response to highly characterized heparin-PF4 antibody-positive plasma/heparin was examined using light transmittance aggregometry, serotonin release, and (125)I-fibrinogen binding assays to human platelets.	Serotonin	284-293	integrin subunit alpha 2b	Homo sapiens	47-52	
17446559-4	2007	Our results showed that serotonin at 200 nM significantly enhanced the expansion of CD34+ cells to early stem/progenitors (CD34+ cells, colony-forming unit-mixed [CFU-GEMM]) and multilineage committed progenitors (burst-forming unit/colony-forming unit-erythroid [BFU/CFU-E], colony-forming unit-granulocyte macrophage, colony-forming unit-megakaryocyte, CD61+ CD41+ cells).	Serotonin	24-33	integrin subunit alpha 2b	Homo sapiens	361-365	
11568009-8	2001	Treatment of particles with thrombin induced serotonin release and aggregation that was blocked by CD41a antibodies.	Serotonin	45-54	integrin subunit alpha 2b	Homo sapiens	99-103	
12693968-3	2003	Suppression of GP IIb-IIIa receptor activity by both preparations led to 100% inhibition of [(14)C]serotonin secretion from dense granules upon platelet activation with ADP, to partial inhibition upon activation with thromboxane A(2) analog U46619 (by 60-70%) and thrombin at 0.1 U/ml (by 40-50%), but did not decrease serotonin secretion induced by thrombin at 1 U/ml.	Serotonin	99-108	integrin subunit alpha 2b	Homo sapiens	15-21	
12693968-3	2003	Suppression of GP IIb-IIIa receptor activity by both preparations led to 100% inhibition of [(14)C]serotonin secretion from dense granules upon platelet activation with ADP, to partial inhibition upon activation with thromboxane A(2) analog U46619 (by 60-70%) and thrombin at 0.1 U/ml (by 40-50%), but did not decrease serotonin secretion induced by thrombin at 1 U/ml.	Serotonin	319-328	integrin subunit alpha 2b	Homo sapiens	15-21	
12693968-5	2003	MonAB CRC54 against GP IIb-IIIa, which induced its interaction with fibrinogen and platelet aggregation, also stimulated serotonin and P-selectin secretion.	Serotonin	121-130	integrin subunit alpha 2b	Homo sapiens	20-26	
12693968-8	2003	Upon platelet activation by concanavalin A (Con A), caused by clusterization of membrane glycoproteins, GP IIb-IIIa blockade only slightly (by 15-20%) decreased serotonin secretion.	Serotonin	161-170	integrin subunit alpha 2b	Homo sapiens	104-110	
1828363-2	1991	Here, we show that platelet activation following addition of a monoclonal antibody directed against GPIIb/IIIa, P256 is completely blocked by IV-3, as monitored by serotonin release, calcium and pH modifications.	Serotonin	164-173	integrin subunit alpha 2b	Homo sapiens	100-105	
1390897-4	1992	The later stage of platelet adhesion was inhibited by an antibody against the GPIIb/IIIa complex and a concomitant release of 14C-labeled serotonin was observed.	Serotonin	138-147	integrin subunit alpha 2b	Homo sapiens	78-83	
9361365-1	1997	Inhibition of aggregation by Ro 44-9883, a potent and selective non-peptide GPIIb/IIIa antagonist, resulted in inhibition of serotonin secretion induced by weak agonists such as ADP or low doses of either thrombin receptor agonist peptide (TRAP) or collagen.	Serotonin	125-134	integrin subunit alpha 2b	Homo sapiens	76-81