PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26053620-7 2015 Activation of the Akt/mTOR pathway in masseter muscle of the DEX-treated group was significantly inhibited compared to that of the Control group, and CB suppressed this inhibition. Dextromethorphan 61-64 AKT serine/threonine kinase 1 Homo sapiens 18-21 26053620-11 2015 These results indicate that CB antagonizes DEX-induced muscle atrophy and fast-to-slow MHC isoform transition via modulation of Akt/mTOR activity and IGF1 expression. Dextromethorphan 43-46 AKT serine/threonine kinase 1 Homo sapiens 128-131 22536436-12 2012 Finally, both LiCl pre-treatment and calpain inhibition prevented the DEX-induced inhibition on the insulin-stimulated Akt phosphorylation. Dextromethorphan 70-73 AKT serine/threonine kinase 1 Homo sapiens 119-122 22536436-13 2012 In conclusion, our study suggests that the tau phosphorylation and mu-calpain activation mediate the DEX-induced inhibition on the insulin-stimulated Akt phosphorylation. Dextromethorphan 101-104 AKT serine/threonine kinase 1 Homo sapiens 150-153 28992584-8 2018 Furthermore, the effects of prenatal DEX exposure and swimming exercise on depression were associated with OGT-related mitochondrial motility, including PINK1/Parkin pathway and AKT/GSK3beta pathway. Dextromethorphan 37-40 AKT serine/threonine kinase 1 Homo sapiens 178-181 23140507-6 2013 DXM abrogated LPS-induced phosphorylation of ERK and Akt. Dextromethorphan 0-3 AKT serine/threonine kinase 1 Homo sapiens 53-56 23140507-9 2013 CONCLUSIONS: Dextromethorphan inhibits the adhesive capacity of HUVECs by reducing the LPS-induced ICAM-1 and VCAM-1 expression via the suppression of the ERK, Akt, and NF-kappaB signaling pathways. Dextromethorphan 13-29 AKT serine/threonine kinase 1 Homo sapiens 160-163 22536436-9 2012 If so, we examined whether the DEX-induced tau phosphorylation and mu-calpain activation mediate the DEX-induced inhibition on the insulin-stimulated Akt phosphorylation. Dextromethorphan 101-104 AKT serine/threonine kinase 1 Homo sapiens 150-153 33204294-8 2020 Besides, Dex could also inhibit the activation of the PI3K/AKT signaling pathway (all P < 0.05), thus affecting cell function, while Berb treatment significantly reversed the expression of those above proteins (all P < 0.05). Dextromethorphan 9-12 AKT serine/threonine kinase 1 Homo sapiens 59-62 33204294-9 2020 Conclusion: Berb attenuated DEX induced reduction of proliferation and migration, oxidative stress, and apoptosis of tendon cells by activating the PI3K/AKT signaling pathway and regulated the expression of phenotype related biomarkers in tendon cells. Dextromethorphan 28-31 AKT serine/threonine kinase 1 Homo sapiens 153-156