PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23781253-8 2013 Remarkably, DXM decreased the LPS-induced surface expression of CD80, CD83, and HLA-DR and the secretion of IL-6 and IL-12 in human monocyte-derived dendritic cells (MDDCs). Dextromethorphan 12-15 interleukin 6 Homo sapiens 108-112 24126150-3 2014 Therefore, the objective of this study was to examine the inhibitory effect of an exogenous GC (dexamethasone, DEX) on leptin- and lipopolysaccharide (LPS)-induced IL-6 production by peripheral blood mononuclear cells (PBMCs) ex vivo in obese subjects compared to normal-weight subjects. Dextromethorphan 111-114 interleukin 6 Homo sapiens 164-168 8937133-1 1996 UNLABELLED: To investigate the effects of disease modifying antirheumatic drugs (DMARDs) and DEX on production of IL-1 beta, IL-6 and TNF-alpha, synovial cells were observed after IL-1 beta administration in vitro. Dextromethorphan 93-96 interleukin 6 Homo sapiens 125-129 8937133-6 1996 RESULTS: DEX inhibited the production of IL-6. Dextromethorphan 9-12 interleukin 6 Homo sapiens 41-45 26640530-13 2015 In the DEX group compared with the control group, IL-1beta, IL-6 and CRP levels were markedly decreased at 6 h and 1 day after surgery (P<0.01). Dextromethorphan 7-10 interleukin 6 Homo sapiens 60-64 32214297-12 2020 A significant decrease of interleukin (IL)-1 beta, IL-6, tumor necrosis factor (TNF)-alpha, and increased CD4+ and CD4+/CD8+ were observed in the DEX group compared with the SUF group at 24 and 48 hours after surgery (P < 0.05). Dextromethorphan 146-149 interleukin 6 Homo sapiens 51-55 32477139-10 2020 IL-6 (P < 0.001) levels were lower in the DEX group at T1, and TNF-alpha (P = 0.003) levels were lower in the DEX group at T1 and T3, but IL-1beta levels were similar between the two groups. Dextromethorphan 42-45 interleukin 6 Homo sapiens 0-4 30887238-1 2019 A physiologically based pharmacokinetic (PBPK) model was used to simulate the impact of elevated levels of interleukin (IL)-6 on the exposure of several orally administered cytochrome P450 (CYP) probe substrates (caffeine, S-warfarin, omeprazole, dextromethorphan, midazolam, and simvastatin). Dextromethorphan 247-263 interleukin 6 Homo sapiens 107-125 25132247-8 2014 In addition, the Dex group had lower serum CK-MB, IL-6, cTnI and GP-BB concentrations than the control group (P < 0.05). Dextromethorphan 17-20 interleukin 6 Homo sapiens 50-54 24126150-9 2014 The suppressive effect of DEX on leptin- and LPS-induced IL-6 production (IC50) was not different between the two groups. Dextromethorphan 26-29 interleukin 6 Homo sapiens 57-61