PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2615413-2 1989 squarrosa antagonized in a concentration-dependent way the contractions of rat duodenum, guinea-pig ileum, rat vas deferens and rat uterus as induced by acetylcholine, histamine, noradrenaline, oxytocin and serotonin. Acetylcholine 153-166 arginine vasopressin Rattus norvegicus 111-114 2565246-0 1989 Role of brain acetylcholine in vasopressin release during osmotic stimulation and hemorrhage. Acetylcholine 14-27 arginine vasopressin Rattus norvegicus 31-42 2737728-8 1989 Treatment of cultures with potassium chloride (56 mM) and acetylcholine chloride (5.5 microM) also resulted in significant decreases in cell vasopressin content. Acetylcholine 58-80 arginine vasopressin Rattus norvegicus 141-152 3720882-5 1986 Microinjected AII or ACh into the region of the SFO excited the activity of putative vasopressin (VP)-secreting units in the PVN. Acetylcholine 21-24 arginine vasopressin Rattus norvegicus 85-96 2895160-8 1988 Neurones producing CRF-41 and AVP responded significantly in a dose-dependent manner to acetylcholine stimulation, whereas those producing SRIF did not. Acetylcholine 88-101 arginine vasopressin Rattus norvegicus 30-33 2895160-9 1988 As cultures matured, the CRF-41- and AVP-producing neurones became more sensitive to acetylcholine with the maximal response at 1 nmol acetylcholine/l. Acetylcholine 85-98 arginine vasopressin Rattus norvegicus 37-40 2895160-9 1988 As cultures matured, the CRF-41- and AVP-producing neurones became more sensitive to acetylcholine with the maximal response at 1 nmol acetylcholine/l. Acetylcholine 135-148 arginine vasopressin Rattus norvegicus 37-40 3960274-4 1986 Use of acetylcholine to selectively stimulate vasopressin neurones appears to evoke a rise in local release of vasopressin but not oxytocin. Acetylcholine 7-20 arginine vasopressin Rattus norvegicus 46-57 3960274-4 1986 Use of acetylcholine to selectively stimulate vasopressin neurones appears to evoke a rise in local release of vasopressin but not oxytocin. Acetylcholine 7-20 arginine vasopressin Rattus norvegicus 111-122 3900818-1 1985 Previous work has shown the vasopressin-secreting cells of the supraoptic nucleus receive a cholinergic input from a region dorsolateral to the nucleus, and that acetylcholine (ACh) activation of these cells is blocked by nicotinic antagonists. Acetylcholine 162-175 arginine vasopressin Rattus norvegicus 28-39 4087976-1 1985 In vas deferens from acute and chronic diabetic rats a hypersensitivity to norepinephrine and acetylcholine was observed. Acetylcholine 94-107 arginine vasopressin Rattus norvegicus 3-6 3900818-1 1985 Previous work has shown the vasopressin-secreting cells of the supraoptic nucleus receive a cholinergic input from a region dorsolateral to the nucleus, and that acetylcholine (ACh) activation of these cells is blocked by nicotinic antagonists. Acetylcholine 177-180 arginine vasopressin Rattus norvegicus 28-39 6147772-3 1984 Its effect on vas deferens is partly mediated via alpha 2-adrenoceptors and due to the released noradrenaline, in guinea pig ileum, however, it seems likely that it releases an unidentified inhibitory substance which, in fact, inhibits the release of acetylcholine, and thereby twitches of the ileum. Acetylcholine 251-264 arginine vasopressin Rattus norvegicus 14-17 4068381-1 1985 Organ culture of rat vas deferens produced supersensitivity to norepinephrine and acetylcholine in contractile response without change in alpha 1-adrenergic and muscarinic acetylcholine receptors. Acetylcholine 82-95 arginine vasopressin Rattus norvegicus 21-24 6519742-5 1984 VP release was assessed on the 4th day of culture during a control hour and during the subsequent hour in the presence of acetylcholine. Acetylcholine 122-135 arginine vasopressin Rattus norvegicus 0-2 6519742-6 1984 Acetylcholine caused a concentration-dependent stimulation of VP release from both types of explants, but the response was significantly greater in the explants from 5- and 8-week-old SHRs than in explants from age-matched WKYs. Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 62-64 6290726-1 1982 Studies were made on developmental changes in phasic contractions of isolated rat vas deferens in response to norepinephrine (NE) and acetylcholine (ACh), which are mediated by alpha-adrenergic and muscarinic cholinergic receptors (alpha-R and m-R). Acetylcholine 134-147 arginine vasopressin Rattus norvegicus 82-85 6645783-0 1983 Acetylcholine potentiation of field stimulated rat vas deferens: a pre-synaptic muscarinic mechanism? Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 51-54 6645783-1 1983 Acetylcholine (ACh) was found to markedly enhance the nerve stimulation induced twitch response of isolated, field-stimulated rat vas deferens (RVD). Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 130-133 6645783-1 1983 Acetylcholine (ACh) was found to markedly enhance the nerve stimulation induced twitch response of isolated, field-stimulated rat vas deferens (RVD). Acetylcholine 15-18 arginine vasopressin Rattus norvegicus 130-133 6290726-1 1982 Studies were made on developmental changes in phasic contractions of isolated rat vas deferens in response to norepinephrine (NE) and acetylcholine (ACh), which are mediated by alpha-adrenergic and muscarinic cholinergic receptors (alpha-R and m-R). Acetylcholine 149-152 arginine vasopressin Rattus norvegicus 82-85 6115624-2 1981 The epididymal portion of the rat vas deferens from normal and castrated rats exhibited clear differences regarding both the threshold and the maximal response to acetylcholine. Acetylcholine 163-176 arginine vasopressin Rattus norvegicus 34-37 6288910-6 1982 After incubation with acetylcholine (10(-4)M), however, cyclic GMP and cyclic AMP levels in the denervated vas deferens were almost the same as in the intact one. Acetylcholine 22-35 arginine vasopressin Rattus norvegicus 107-110 6115624-5 1981 The results obtained suggest that low doses of acetylcholine may affect the contractile function of the isolated epididymal portion of rat vas deferens by producing a release of norepinephrine from presynaptic sites and acts in a similar fashion on preparations from both normal and castrated animals. Acetylcholine 47-60 arginine vasopressin Rattus norvegicus 139-142 6115624-3 1981 Alpha adrenoceptor antagonists, hexamethonium and 6-hydroxydopamine diminished the effectiveness of low acetylcholine concentrations on normal and castrated preparations of the epididymal portion of isolated rat vas deferens, but did not influence the maximal response. Acetylcholine 104-117 arginine vasopressin Rattus norvegicus 212-215 747468-0 1978 Regional differences in the effects of denervation, cocaine and chronic reserpine administration on the responses of the rat vas deferens to norepinephrine and acetylcholine. Acetylcholine 160-173 arginine vasopressin Rattus norvegicus 125-128 510363-0 1979 Enhancement by elevated external potassium of the maximal responses to acetylcholine and norepinephrine in the rat vas deferens. Acetylcholine 71-84 arginine vasopressin Rattus norvegicus 115-118 510363-1 1979 In the rat vas deferens, the maximal response to acetylcholine increased almost linearly as a function of external potassium concentration, [K+]0. Acetylcholine 49-62 arginine vasopressin Rattus norvegicus 11-14 436724-1 1979 Acetylcholine and nicotine stimulated vasopressin (VP) release from the organ-cultured rat hypothalamo-neurohypophyseal system (HNS). Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 38-49 436724-1 1979 Acetylcholine and nicotine stimulated vasopressin (VP) release from the organ-cultured rat hypothalamo-neurohypophyseal system (HNS). Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 51-53 436724-2 1979 Nicotinic antagonists, hexamethonium, tetraethylammonium chloride, and trimethaphan blocked VP release in response to acetylcholine and nicotine. Acetylcholine 118-131 arginine vasopressin Rattus norvegicus 92-94 747468-1 1978 The prostatic half and epididymal half of the rat vas deferens was found to show the difference with respect to both the sensitivity (expressed as the geometric mean ED50) and maximal response to norepinephrine and acetylcholine. Acetylcholine 215-228 arginine vasopressin Rattus norvegicus 50-53 1248509-5 1976 Cocaine also enhanced the reactivity of the vas deferens to acetylcholine. Acetylcholine 60-73 arginine vasopressin Rattus norvegicus 44-47 41869-3 1978 Acetylcholine and histamine stimulated the release of AVP at the hypothalamic and pituitary levels; dopamine and norepinephrine released AVP in a dose related manner only from the hypothalamus; angiotensin II released AVP in the same fashion only from the pituitary gland. Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 54-57 988183-10 1976 The fact that the isolated hypothalamus can be stimulated by dopamine and acetylcholine to release increased amount of oxytocin and arginine vasopressin raises the question of the origin and fate of the hormones released in this way. Acetylcholine 74-87 arginine vasopressin Rattus norvegicus 141-152 1252961-4 1976 These results were interpreted as being consistent with the idea of a dopamine-acetylcholine antagonism in the VAS whose net output modulate behavioral inhibition. Acetylcholine 79-92 arginine vasopressin Rattus norvegicus 111-114 1248509-6 1976 The basis of this enhancement by cocaine of the reactivity of the vas deferens to acetylcholine remains to be established, but clearly is not mediated postjunctionally since responses to carbachol were not similarly affected. Acetylcholine 82-95 arginine vasopressin Rattus norvegicus 66-69 1143365-6 1975 Acetylcholine 5.5x10-4M neither alone nor in the presence of atropine 2.9x10-6M changed the "resting" release of vasopressin. Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 113-124 1123719-1 1975 Chronic postganglionic denervation of the rate vas deferens produces an increase in the sensitivity of the in vitro smooth muscle to norepinephrine, methoxamine, acetylcholine, potassium and electrical stimulation. Acetylcholine 162-175 arginine vasopressin Rattus norvegicus 47-50 4262279-0 1972 Acetylcholine release from isolated vas deferens of the rat. Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 36-39 4823462-3 1974 The effects of noradrenaline and 5-hydroxytryptamine are blocked by phentolamine and methysergide respectively.3 The cat anococcygeus is relaxed by acetylcholine, carbachol, isoprenaline, ATP, prostaglandins E(1), E(2) and F(2alpha) and vasopressin, all of which contract the rat muscle. Acetylcholine 148-161 arginine vasopressin Rattus norvegicus 237-248 5536396-0 1970 Vasopressin release from the rat supraoptico-neurohypophysial system in vitro in response to hypertonicity and acetylcholine. Acetylcholine 111-124 arginine vasopressin Rattus norvegicus 0-11 15963537-3 2005 Microinjection of acetylcholine (ACh) into the lateral septal area (LSA) of unanesthetized rats caused similar vasopressin-related pressor responses. Acetylcholine 18-31 arginine vasopressin Rattus norvegicus 111-122 34021245-0 2021 Top-down acetylcholine signaling via olfactory bulb vasopressin cells contributes to social discrimination in rats. Acetylcholine 9-22 arginine vasopressin Rattus norvegicus 52-63 34021245-4 2021 Finally, cholinergic activation of the vasopressin system contributes to vasopressin-dependent social discrimination, since recognition of a known rat was blocked by bulbar infusion of the muscarinic acetylcholine receptor antagonist atropine and rescued by additional bulbar application of vasopressin. Acetylcholine 200-213 arginine vasopressin Rattus norvegicus 39-50 34021245-4 2021 Finally, cholinergic activation of the vasopressin system contributes to vasopressin-dependent social discrimination, since recognition of a known rat was blocked by bulbar infusion of the muscarinic acetylcholine receptor antagonist atropine and rescued by additional bulbar application of vasopressin. Acetylcholine 200-213 arginine vasopressin Rattus norvegicus 73-84 34021245-4 2021 Finally, cholinergic activation of the vasopressin system contributes to vasopressin-dependent social discrimination, since recognition of a known rat was blocked by bulbar infusion of the muscarinic acetylcholine receptor antagonist atropine and rescued by additional bulbar application of vasopressin. Acetylcholine 200-213 arginine vasopressin Rattus norvegicus 73-84 19022248-8 2009 Acetylcholine elicited a strong contraction in control vas deferens, but only a small response was obtained in the reinnervated transplant. Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 55-58 17579789-0 2007 ACh-evoked membrane hyperpolarization in smooth muscle cells of rat vas deferens in vitro: involvement of K(+) channels and NO. Acetylcholine 0-3 arginine vasopressin Rattus norvegicus 68-71 17579789-1 2007 To explore the underlying mechanism of acetylcholine (ACh)-evoked membrane hyperpolarizing response in isolated rat vas deferens smooth muscle cells (SMCs), intracellular microelectrode recording technique and intracellular microelectrophoresis fluorescent staining technique were used to study ACh-evoked membrane hyperpolarizing response in SMCs freshly isolated from Wistar rat vas deferens. Acetylcholine 39-52 arginine vasopressin Rattus norvegicus 116-119 17579789-1 2007 To explore the underlying mechanism of acetylcholine (ACh)-evoked membrane hyperpolarizing response in isolated rat vas deferens smooth muscle cells (SMCs), intracellular microelectrode recording technique and intracellular microelectrophoresis fluorescent staining technique were used to study ACh-evoked membrane hyperpolarizing response in SMCs freshly isolated from Wistar rat vas deferens. Acetylcholine 39-52 arginine vasopressin Rattus norvegicus 381-384 17579789-1 2007 To explore the underlying mechanism of acetylcholine (ACh)-evoked membrane hyperpolarizing response in isolated rat vas deferens smooth muscle cells (SMCs), intracellular microelectrode recording technique and intracellular microelectrophoresis fluorescent staining technique were used to study ACh-evoked membrane hyperpolarizing response in SMCs freshly isolated from Wistar rat vas deferens. Acetylcholine 54-57 arginine vasopressin Rattus norvegicus 116-119 17579789-1 2007 To explore the underlying mechanism of acetylcholine (ACh)-evoked membrane hyperpolarizing response in isolated rat vas deferens smooth muscle cells (SMCs), intracellular microelectrode recording technique and intracellular microelectrophoresis fluorescent staining technique were used to study ACh-evoked membrane hyperpolarizing response in SMCs freshly isolated from Wistar rat vas deferens. Acetylcholine 54-57 arginine vasopressin Rattus norvegicus 381-384 17579789-9 2007 The results suggest that ACh-evoked membrane hyperpolarization in rat vas deferens SMCs is mediated by M(3) receptor followed with activation of K(ATP) channels, K(ir) channels, and NO release. Acetylcholine 25-28 arginine vasopressin Rattus norvegicus 70-73 5767890-4 1969 In addition, these units are excited by intracarotid injections of carbachol, acetylcholine and NaCl (5%) which are less effective stimuli for vasopressin release.3. Acetylcholine 78-91 arginine vasopressin Rattus norvegicus 143-154 19948196-0 2010 Arginine vasopressin induces rat caudate nucleus releasing acetylcholine to participate in pain modulation. Acetylcholine 59-72 arginine vasopressin Rattus norvegicus 9-20 15963537-3 2005 Microinjection of acetylcholine (ACh) into the lateral septal area (LSA) of unanesthetized rats caused similar vasopressin-related pressor responses. Acetylcholine 33-36 arginine vasopressin Rattus norvegicus 111-122 11716821-2 2001 Acetylcholine is known to excite SON neurons and to increase vasopressin release. Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 61-72 12031853-2 2002 injection of choline (50-150 microg), a precursor of the neurotransmitter acetylcholine, produced a time-and dose-dependent increase in plasma vasopressin levels in conscious, freely moving rats. Acetylcholine 74-87 arginine vasopressin Rattus norvegicus 143-154 12458034-0 2002 Specific up-regulation of CRH or AVP secretion by acetylcholine or lipopolysaccharide in inflammatory susceptible Lewis rat fetal hypothalamic cells. Acetylcholine 50-63 arginine vasopressin Rattus norvegicus 33-36 8418984-8 1993 L-NAME and methylene blue partially inhibited acetylcholine-induced relaxation of vasopressin-contracted vessels from both strains. Acetylcholine 46-59 arginine vasopressin Rattus norvegicus 82-93 11557616-2 2001 Acetylcholine is known to excite SON neurons and to elicit vasopressin release. Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 59-70 10462183-5 1999 These findings demonstrate that AVP4-9 stimulates ACh release via mediation by V1-like vasopressin receptors, and shows dependence on calcium ion and temperature. Acetylcholine 50-53 arginine vasopressin Rattus norvegicus 87-98 8891595-13 1996 It is concluded that the precursor of acetylcholine, choline, can increase blood pressure and reverse hypotension in alpha-adrenoceptor or ganglionic transmission blocked rats, by increasing plasma vasopressin. Acetylcholine 38-51 arginine vasopressin Rattus norvegicus 198-209 10658610-1 2000 Acetylcholine can stimulate the release of vasopressin. Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 43-54 10658610-2 2000 In organ-cultured hypothalamo-neurohypophyseal systems, acetylcholine enhanced vasopressin release by acting in or near the supraoptic nucleus Extracellular recordings suggested that acetylcholine can increase supraoptic neuron excitability. Acetylcholine 56-69 arginine vasopressin Rattus norvegicus 79-90 10658610-2 2000 In organ-cultured hypothalamo-neurohypophyseal systems, acetylcholine enhanced vasopressin release by acting in or near the supraoptic nucleus Extracellular recordings suggested that acetylcholine can increase supraoptic neuron excitability. Acetylcholine 183-196 arginine vasopressin Rattus norvegicus 79-90 8418984-12 1993 Vasopressin, on the other hand, does not elicit production of this contracting factor and may enhance the vasorelaxant action of acetylcholine in resistance arteries of both strains via actions on endothelial or vascular smooth muscle cells. Acetylcholine 129-142 arginine vasopressin Rattus norvegicus 0-11 1877699-0 1991 Interactions between brain acetylcholine and prostaglandins in control of vasopressin release. Acetylcholine 27-40 arginine vasopressin Rattus norvegicus 74-85 1941613-7 1991 Acetylcholine produced depressor responses in the presence of 5-hydroxy-tryptamine or vasopressin, but clonidine did not. Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 86-97 1877699-1 1991 We have examined in conscious rats the interaction between centrally acting prostanoids and acetylcholine in the stimulation of vasopressin secretion. Acetylcholine 92-105 arginine vasopressin Rattus norvegicus 128-139 1877699-6 1991 We conclude that the stimulation of vasopressin release by centrally acting acetylcholine is dependent on increased prostanoid biosynthesis. Acetylcholine 76-89 arginine vasopressin Rattus norvegicus 36-47 1681990-5 1991 Acetylcholine at concentrations of 1 to 100 nM caused a dose-dependent, rapid increase in AVP, whereas AVP release induced by 10 nM acetylcholine was completely suppressed by the combined presence of 10 microM hexamethonium, a nicotinic receptor antagonist, and 50 microM atropine, a muscarinic receptor antagonist. Acetylcholine 0-13 arginine vasopressin Rattus norvegicus 90-93 1681990-5 1991 Acetylcholine at concentrations of 1 to 100 nM caused a dose-dependent, rapid increase in AVP, whereas AVP release induced by 10 nM acetylcholine was completely suppressed by the combined presence of 10 microM hexamethonium, a nicotinic receptor antagonist, and 50 microM atropine, a muscarinic receptor antagonist. Acetylcholine 132-145 arginine vasopressin Rattus norvegicus 103-106