PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10095042-10	1999	The effects of 5 microM muscimol to increase GnRH pulsatility were blocked by co-exposure to the GABAA receptor antagonist, bicuculline.	Bicuculline	124-135	gonadotropin releasing hormone 1	Homo sapiens	45-49	
9629249-13	1998	This concept is supported by blockade of GMCSF-induced suppression of LHRH release from medial basal hypothalamic explants by the GABAa receptor blocker, bicuculline.	Bicuculline	154-165	gonadotropin releasing hormone 1	Homo sapiens	70-74	
9713333-8	1998	Both PREG-S and bicuculline overcame the inhibitory effects of allopregnanolone on GnRH release, whereas DHEAS did not.	Bicuculline	16-27	gonadotropin releasing hormone 1	Homo sapiens	83-87	
18434046-1	2009	The effect of prolonged, intermittent infusion of GABA(A) receptor agonist (muscimol) or GABA(A) receptor antagonist (bicuculline) into the third cerebral ventricle on the expression of GnRH gene and GnRH-R gene in the hypothalamus and GnRH-R gene in the anterior pituitary gland was examined in follicular-phase ewes by real-time PCR.	Bicuculline	118-129	gonadotropin releasing hormone 1	Homo sapiens	186-190	
9483201-12	1997	This concept is supported by a blockade of GM-CSF-induced suppression of LHRH release from medial basal hypothalamic explants by the GABA-A receptor blocker, bicuculline.	Bicuculline	158-169	gonadotropin releasing hormone 1	Homo sapiens	73-77	
8278400-3	1994	Bicuculline, but not saclofen, induced a large and prompt increase in LHRH release in prepubertal monkeys, whereas it stimulated LHRH release slightly in pubertal monkeys.	Bicuculline	0-11	gonadotropin releasing hormone 1	Homo sapiens	70-74	
8278400-3	1994	Bicuculline, but not saclofen, induced a large and prompt increase in LHRH release in prepubertal monkeys, whereas it stimulated LHRH release slightly in pubertal monkeys.	Bicuculline	0-11	gonadotropin releasing hormone 1	Homo sapiens	129-133	
20456608-5	2010	Our recent work indicates that blocking endogenous GABA inhibition with the GABA(A) receptor blocker, bicuculline, dramatically increases kisspeptin release, which plays an important role in the pubertal increase in GnRH release.	Bicuculline	102-113	gonadotropin releasing hormone 1	Homo sapiens	216-220	
18434046-4	2009	The decrease or increase of GnRH-R mRNA in the anterior pituitary gland and LH secretion in the muscimol- or bicuculline-treated ewes, respectively, is probably a consequence of parallel changes in the release of GnRH from the hypothalamus activating GnRH-R gene expression.	Bicuculline	109-120	gonadotropin releasing hormone 1	Homo sapiens	28-32	
18312488-5	2008	However, GnRH increased (p < 0.05) after exposure to 10 mM GABA(A or B) antagonists (bicuculline or CGP52432, respectively).	Bicuculline	88-99	gonadotropin releasing hormone 1	Homo sapiens	9-13	
16543268-5	2006	GnRH neurons exhibited robust currents in response to millimolar concentrations of GABA and a picrotoxin (PTX)-sensitive, bicuculline-insensitive current that probably arises from spontaneous openings of GABAA receptors.	Bicuculline	122-133	gonadotropin releasing hormone 1	Homo sapiens	0-4	
14981261-4	2004	In the present work, bicuculline, a GABAergic antagonist, completely prevented the inhibition of AEA (10(-9)M) on N-methyl-D-aspartic acid-induced LHRH release, but naltrexone, a micro-opioid receptor antagonist, had no effect.	Bicuculline	21-32	gonadotropin releasing hormone 1	Homo sapiens	147-151