PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2831223-3 1988 Several observations indicate that the exchanger is regulated by protein kinase C. (i) Inhibitors of protein kinase C (trifluoperazine, sphingosine) inhibit the increase in pHi seen during thrombin stimulation as well as Ca2+ mobilization; artificially increasing pHi by monensin or NH4Cl then restores Ca2+ mobilization. Monensin 271-279 coagulation factor II, thrombin Homo sapiens 189-197 3027576-4 1987 We also demonstrate that cytoplasmic alkalinization produced by exposure to the ionophore monensin sensitizes the human platelet response to stimulation by thrombin resulting in enhanced Ca2+ mobilization and aggregability. Monensin 90-98 coagulation factor II, thrombin Homo sapiens 156-164