PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15540782-4 2004 MATERIALS AND METHODS: Initial screening for enhancement of the inhibitory effects of MMC, cisplatin and gemcitabine on viability by treatment with the 2 hTERT AS-ODNs ASt2206 and ASt2331 was performed in 4 TCC cell lines prior to CT. Apoptosis was assessed by annexin V staining and detection of activated caspase-3 using Western blot analysis. Mitomycin 86-89 telomerase reverse transcriptase Homo sapiens 154-159 16615118-8 2006 Furthermore, the suppression of hTERT by siRNAs caused an enhancement of the antiproliferative capacity of the chemotherapeutics mitomycin C and cisplatin. Mitomycin 129-140 telomerase reverse transcriptase Homo sapiens 32-37 15608686-5 2005 Similarly, constitutive hTERT expression inhibited wild-type p53-dependent apoptosis in response to mitomycin C or 5-fluorouracil in HCT116 colon carcinoma cells carrying endogenous p53. Mitomycin 100-111 telomerase reverse transcriptase Homo sapiens 24-29