PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11338180-2	2001	We studied the expression and localization of annexin VII (synexin), a Ca(2+)-/GTP-dependent membrane fusion protein, in the human CNS.	Guanosine Triphosphate	79-82	annexin A7	Homo sapiens	46-57	
11994295-0	2002	Protein kinase C and guanosine triphosphate combine to potentiate calcium-dependent membrane fusion driven by annexin 7.	Guanosine Triphosphate	21-43	annexin A7	Homo sapiens	110-119	
11994295-2	2002	Guanosine triphosphate (GTP) and its non-hydrolyzable analogues optimally enhance the phosphorylation of annexin 7 by protein kinase C in vitro.	Guanosine Triphosphate	0-22	annexin A7	Homo sapiens	105-114	
11994295-2	2002	Guanosine triphosphate (GTP) and its non-hydrolyzable analogues optimally enhance the phosphorylation of annexin 7 by protein kinase C in vitro.	Guanosine Triphosphate	24-27	annexin A7	Homo sapiens	105-114	
11994295-3	2002	Reciprocally, phosphorylation by protein kinase C significantly potentiates the binding and hydrolysis of GTP by annexin 7.	Guanosine Triphosphate	106-109	annexin A7	Homo sapiens	113-122	
11338180-2	2001	We studied the expression and localization of annexin VII (synexin), a Ca(2+)-/GTP-dependent membrane fusion protein, in the human CNS.	Guanosine Triphosphate	79-82	annexin A7	Homo sapiens	59-66	
10570150-1	1999	The mammalian anx7 gene codes for a Ca(2+)-activated GTPase, which supports Ca(2+)/GTP-dependent secretion events and Ca(2+) channel activities in vitro and in vivo.	Guanosine Triphosphate	53-56	annexin A7	Homo sapiens	14-18	
11278415-1	2001	Annexin 7, a Ca(2+)/GTP-activated membrane fusion protein, is preferentially phosphorylated in intact chromaffin cells, and the levels of annexin 7 phosphorylation increase quantitatively in proportion to the extent of catecholamine secretion.	Guanosine Triphosphate	20-23	annexin A7	Homo sapiens	0-9	
10875895-1	2000	ANX7 is a Ca(2+)/GTP-dependent membrane fusion protein, which is involved in regulating exocytotic secretion.	Guanosine Triphosphate	17-20	annexin A7	Homo sapiens	0-4	
9918499-6	1998	In addition, annexin VII showed hydrolytic activity towards GTP, and similarities in the mechanism of action to that of small GTP-binding proteins were found.	Guanosine Triphosphate	60-63	annexin A7	Homo sapiens	13-24	
9918499-6	1998	In addition, annexin VII showed hydrolytic activity towards GTP, and similarities in the mechanism of action to that of small GTP-binding proteins were found.	Guanosine Triphosphate	126-129	annexin A7	Homo sapiens	13-24	
9327852-0	1998	Synexin (annexin VII) hypothesis for Ca2+/GTP-regulated exocytosis.	Guanosine Triphosphate	42-45	annexin A7	Homo sapiens	0-7	
9327852-0	1998	Synexin (annexin VII) hypothesis for Ca2+/GTP-regulated exocytosis.	Guanosine Triphosphate	42-45	annexin A7	Homo sapiens	9-20	
8855260-0	1996	Membrane fusion protein synexin (annexin VII) as a Ca2+/GTP sensor in exocytotic secretion.	Guanosine Triphosphate	56-59	annexin A7	Homo sapiens	24-31	
8855260-0	1996	Membrane fusion protein synexin (annexin VII) as a Ca2+/GTP sensor in exocytotic secretion.	Guanosine Triphosphate	56-59	annexin A7	Homo sapiens	33-44	
8855260-2	1996	However, the calcium-dependent membrane fusion reaction driven by synexin (annexin VII) is an in vitro model for this process, which we have now found to be further activated by GTP.	Guanosine Triphosphate	178-181	annexin A7	Homo sapiens	66-73	
8855260-2	1996	However, the calcium-dependent membrane fusion reaction driven by synexin (annexin VII) is an in vitro model for this process, which we have now found to be further activated by GTP.	Guanosine Triphosphate	178-181	annexin A7	Homo sapiens	75-86	
8855260-3	1996	The mechanism of fusion activation depends on the unique ability of synexin to bind and hydrolyze GTP in a calcium-dependent manner, both in vitro and in vivo in streptolysin O-permeabilized chromaffin cells.	Guanosine Triphosphate	98-101	annexin A7	Homo sapiens	68-75	
8855260-4	1996	The required [Ca2+] for GTP binding by synexin is in the range of 50-200 microM, which is known to occur at exocytotic sites in chromaffin cells, neurons, and other cell types.	Guanosine Triphosphate	24-27	annexin A7	Homo sapiens	39-46	
8855260-5	1996	Previous immunolocalization studies place synexin at exocytotic sites in chromaffin cells, and we conclude that synexin is an atypical G protein that may be responsible for both detecting and mediating the Ca2+/GTP signal for exocytotic membrane fusion.	Guanosine Triphosphate	211-214	annexin A7	Homo sapiens	112-119