PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8610637-2 1996 A phase II trial of a continuous infusion of cisplatin, 5-FU, and high dose folinic acid (PFL) as induction chemotherapy in patients with previously untreated, locally advanced HN cancer was performed in an attempt to confirm the encouraging results reported by Dana Farber investigators using an identical regimen. Leucovorin 76-88 profilin 2 Homo sapiens 90-93 12598339-1 2003 BACKGROUND: To study prospectively the activity of primary chemotherapy with cisplatin, fluorouracil and leucovorin (PFL) in patients with paranasal cancer receiving surgery and postoperative radiotherapy. Leucovorin 105-115 profilin 2 Homo sapiens 117-120 12598339-3 2003 PFL (leucovorin 250 mg/m2/day for 5 days as a 120 h continuous infusion (c.i. Leucovorin 5-15 profilin 2 Homo sapiens 0-3 9166490-1 1995 PURPOSE: The combination of cisplatin, 5-fluorouracil, and leucovorin (PFL) has been reported to have a 29% response rate in advanced non-small cell lung cancer. Leucovorin 59-69 profilin 2 Homo sapiens 71-74 8635020-1 1995 BACKGROUND: Cisplatin, 5-flourouracil (5-FU), and leucovorin (PFL) chemotherapy has been reported to be effective in the treatment of cancers but severe mucositis or neutropenia are dose limiting toxicities. Leucovorin 50-60 profilin 2 Homo sapiens 62-65 8748007-0 1996 Pilot study of ambulatory infusional delivery of a multidrug regimen: cisplatin, 5-fluorouracil and leucovorin (PFL) +/- etoposide. Leucovorin 100-110 profilin 2 Homo sapiens 112-115 8293384-3 1994 Based on high response rates of Cisplatin, 5-Fluororacil and Leucovorin (PFL) in patients with advanced squamous cell cancers of the head and neck, we tested a new outpatient PFL chemotherapy program in patients with advanced NPC. Leucovorin 61-71 profilin 2 Homo sapiens 73-76 8313319-1 1994 BACKGROUND: Cisplatin, 5-fluorouracil, and leucovorin (PFL) have demonstrated synergistic activity in preclinical models. Leucovorin 43-53 profilin 2 Homo sapiens 55-58 7973772-1 1994 In a randomized phase II study by the Cancer and Leukemia Group B, the cisplatin/5-fluorouracil/leucovorin (PFL) combination produced a 29% response rate in advanced, unresectable non-small cell lung cancer. Leucovorin 96-106 profilin 2 Homo sapiens 108-111 1688926-2 1990 Therefore, the addition of LV to cisplatin and 5-FU (PFL) may increase the activity of that combination in head and neck cancer. Leucovorin 27-29 profilin 2 Homo sapiens 53-56 8274261-2 1994 OBJECTIVE: To evaluate the activity and toxicity of the drug combination cisplatin, fluorouracil by continuous infusion, and high-dose oral leucovorin calcium (PFL) as induction chemotherapy in patients with advanced and untreated squamous cell head and neck (SCHN) cancer. Leucovorin 140-158 profilin 2 Homo sapiens 160-163 2297193-1 1990 STUDY OBJECTIVE: To study the activity of continuous infusion cisplatin, 5-fluorouracil, and high-dose leucovorin (PFL) as induction chemotherapy in patients with previously untreated, advanced squamous cell carcinoma of the head and neck. Leucovorin 103-113 profilin 2 Homo sapiens 115-118 8426214-1 1993 PURPOSE: To increase the activity of cisplatin, fluorouracil (5-FU), and leucovorin (PFL) through further biochemical modulation and study the pharmacologic interaction of 5-FU and interferon alfa-2b (IFN). Leucovorin 73-83 profilin 2 Homo sapiens 85-88 21612748-7 2011 Here we re port a case of a 64-year-old Taiwanese male patient with neuroendocrine carcinoma of the gall bladder who received combined chemoradiotherapy (CCRT) with cisplatin, 5- fluorouracil and leucovorin (PFL) from June 2009 un til now, and whose disease is stable. Leucovorin 196-206 profilin 2 Homo sapiens 208-211